FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\nkdNR1.UAS.Tag:MYC
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General Information
Symbol
Dmel\nkdNR1.UAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0146976
Feature type
allele
Associated gene
Dmel\nkd
Associated Insertion(s)
Carried in Construct
P{UAS-nkd.NR1.mycC}
Key Links
Transgenic product class
inframe_deletion
(Rousset et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Rousset et al., 2002)
Mutagen
in vitro construct
(Rousset et al., 2002)
Progenitor genotype
Carried in construct
P{UAS-nkd.NR1.mycC}
Cytology
Description

UASt regulatory sequences drive expression of nkd which lacks amino acid residues 179-928 and is tagged at the C-terminal end with Tag:MYC.

(Waldrop et al., 2006)

UAS regulatory sequences drive expression of amino acids 1 to 178 of nkd.

(Rousset et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
UASt
Encoded product / tool
nkd
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of nkdNR1.Scer\UAS under the control of Scer\GAL4B119 does not result in loss of sternite bristles, and in 3 of 5 P{UAS-nkd.NR1} lines tested, the number of sternite bristles appears to be increased.

      (Rousset et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      Scer\GAL4da.G32/nkdNR1.UAS.Tag:MYC fails to rescue nkd3/nkd2

      (Waldrop et al., 2006)

      Scer\GAL4da.G32/nkdNR1.UAS.Tag:MYC fails to rescue nkd3/nkd2

      (Rousset et al., 2002)
      Comments

      Expression of nkdNR1.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4da.G32 fails to rescue the cuticle defects of nkd2/nkd3 embryos.

      (Waldrop et al., 2006)

      Does not rescue the cuticle defects of nkd2/nkd3 embryos when expressed under the control of Scer\GAL4da.G32.

      (Rousset et al., 2002)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      NkdNR1/mycC
      (Waldrop et al., 2006)
      nkdNR1.Scer\UAS.T:Hsap\MYC
      nkdNR1.Scer\UAS
      nkdNR1.UAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (2)