FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\fngL73
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General Information
Symbol
Dmel\fngL73
Species
D. melanogaster
Name
FlyBase ID
FBal0147144
Feature type
allele
Associated gene
Dmel\fng
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Correia et al., 2003)
Progenitor genotype
Cytology
Description

Nucleotide substitution: G?A.

(Correia et al., 2003)

Amino acid replacement: W181term.

(Correia et al., 2003)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3L:20,936,710..20,936,710 [-]
Nucleotide change:

G20936710A

Reported nucleotide change:

G?A

Amino acid change:

W181term | fng-PA

Reported amino acid change:

W181term

(Correia et al., 2003)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      fngL73 mutant female germline stem cells (GSCs) do not undergo the natural turnover seen in wild type: at three weeks after clone induction more fngL73 mutant GSCs are still present in the niche in comparison with wild type controls.

      The contact area between fngL73 mutant female germline stem cells and the niche is greater than in wild type controls at two weeks after clone induction.

      (Tseng et al., 2014)

      The overall number and positioning of the longitudinal glia in fngL73/fng13 embryos is normal.

      (Thomas and van Meyel, 2007)

      fngL73/fngM69 animals that survive to adulthood when grown at 18oC exhibit a strong wing phenotype. fngL73/fng52 animals that survive to adulthood exhibit a strong wing phenotype. fngL73/fng2 animals that survive to adulthood exhibit a strong wing phenotype.

      (Correia et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      fngL73
      (Pandey et al., 2019, LeBon et al., 2014, Stacey et al., 2010, Thomas and van Meyel, 2007)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)