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General Information
Symbol
Dmel\fng80
Species
D. melanogaster
Name
FlyBase ID
FBal0034617
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Deletion removing P element and approximately 10kb of flanking DNA.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

fng80/+ flies have normal wings.

fng80 mutants have extra denticles on the abdomen. These denticles lack orientation and are interspersed with the normally-formed denticle rows 2-4.

Transheterozygous fng2/fng80 females have ovaries showing 0% compound follicles, 26% with long stalks 48% of follicles have abnormal epithelium. The long stalk phenotype is sometimes accompanied by a stalk disorganization phenotype.

Mutant clones induced in the equator or dorsal region of the developing eye do not show significant polarity changes either inside or outside the clone boundary. Mutant clones induced in the ventral domain (close to or far from the equator) caused polarity reversals extending up to four ommatidia from the clone boundary. The shift in chirality is observed only outside the clone boundaries towards the normal equator. Photoreceptor numbers are affected in 24% of ommatidia.

fng80/fng52 mutants are weakly viable and exhibit a severe wing margin loss phenotype.

Mutant clones in the wing reveal ectopic wing margins along clone borders, composed of both wild type and mutant cells. Ectopic margins are composed of a mirror image duplication of dorsal-type bristles. Clone boundaries farther from the normal margin often partially or completely fail to induce ectopic margins. Clones contained with the dorsal surface can be associated with an expansion of the dorsal wing surface. The size of distal outgrowths varies with their location in the wing. Some clones are associated with loss of tissue from the wing margin and reduction in size of the wing. fng+ is not autonomously required for wing cell viability.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference

fng[+]/fng80 is an enhancer of visible | dominant phenotype of Bx1

fng80 is an enhancer of visible | dominant phenotype of Bx1

Phenotype Manifest In
Suppressed by
Statement
Reference

fng80 has denticle | ectopic phenotype, suppressible by SerRX82

Enhancer of
Statement
Reference

fng[+]/fng80 is an enhancer of wing margin phenotype of Bx2

fng[+]/fng80 is an enhancer of wing margin phenotype of Bx1

fng80 is an enhancer of wing phenotype of Bx1

NOT Suppressor of
Statement
Reference

fng80 is a non-suppressor of denticle row 3 phenotype of SerRX82

fng80 is a non-suppressor of denticle row 4 phenotype of SerRX82

Additional Comments
Genetic Interactions
Statement
Reference

SerRX82, fng80 double mutants show the same denticle row phenotype as SerRX82 single mutants, in which a denticle row is missing.

The severity of the Bx1/+ wing scalloping phenotype is enhanced by one copy of fng80.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to complement
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

One of 28 lethal alleles recovered from fng1.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (16)