FB2026_02 , released June 18, 2026
Allele: Dmel\Gγ1UAS.cFa
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General Information
Symbol
Dmel\Gγ1UAS.cFa
Species
D. melanogaster
Name
FlyBase ID
FBal0147909
Feature type
allele
Associated gene
Dmel\Gγ1
Associated Insertion(s)
Carried in Construct
P{UAS-Gγ1.F}
Also Known As
UAS-Gγ1
Key Links
Transgenic product class
wild_type
(Fuse et al., 2003)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Fuse et al., 2003)
Mutagen
in vitro construct
(Fuse et al., 2003)
Progenitor genotype
Carried in construct
P{UAS-Gγ1.F}
Cytology
Description

UASt sequences drive expression of Gγ1.

(Fuse et al., 2003)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Gγ1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Gβ13FScer\UAS.cFa expressed in S2 cells (driven by Scer\GAL4Act5C.PHb) has no effect on the mitotic spindle.

      (Fuse et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Simultaneous expression of Gβ13FScer\UAS.cFa and Gγ1Scer\UAS.cFa (driven by Scer\GAL4mat.αTub67C.T:Hsim\VP16) drastically reduced microtubule organisation in the neuroblast. A metaphase mutant neuroblasts form a small symmetric or disorganised spindle, as though both spindle halves are basal. As a result, some telophase neuroblasts undergo equal cleavage, but others also frequently show defective cytokinesis. Gβ13FScer\UAS.cFa and Gγ1Scer\UAS.cFa simultaneously expressed in S2 cells (driven by Scer\GAL4Act5C.PHb) the mitotic spindle becomes shrunken.

      (Fuse et al., 2003)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Gγ1Scer\UAS.cFa
      Gγ1UAS.cFa
      Name Synonyms
      Secondary FlyBase IDs
        References (4)