FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\tslCBB.bcd
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General Information
Symbol
Dmel\tslCBB.bcd
Species
D. melanogaster
Name
FlyBase ID
FBal0150201
Feature type
allele
Associated gene
Dmel\tsl
Associated Insertion(s)
Carried in Construct
P{bcd.tsl.CBB}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Stevens et al., 2003)
Progenitor genotype
Carried in construct
P{bcd.tsl.CBB}
Cytology
Description

Construct: bcd promoter sequences drive expression of tsl with a Xenopus β-globin leader and bcd 3' sequences (not including those required for anterior localisation).

(Stevens et al., 2003)
Allele components
Component
Use(s)
Regulatory region(s)
tsl
Encoded product / tool
tsl
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      tslCBB.bcd, osk6, tslPZRev32 is a suppressor of embryo | maternal effect phenotype of bcd6

      (Stevens et al., 2003)

      tslCBB.bcd, bcd6, tslPZRev32 is a suppressor of embryo | maternal effect phenotype of osk6

      (Stevens et al., 2003)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      tslCBB.bcd rescues tslPZRev32

      (Stevens et al., 2003)
      Comments

      The addition of tslCBB.bcd completely restores terminal cuticular structures to embryos laid by tslPZRev32 mutant mothers. Embryos produced by bcd6, osk6 and tslPZRev32 mutant mothers lack all anterior posterior patterning. This phenotype is partially rescued by the addition of tslCBB.bcd, leading to embryos that differentiate filzkorper material, at one or both poles.

      (Stevens et al., 2003)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      tslCBB.bcd
      Name Synonyms
      Secondary FlyBase IDs
        References (1)