FlyBase Allele Report: Dmel\stnA[UAS.cEa]

General Information

Symbol

Dmel\stnA^UAS.cEa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Estes

FlyBase ID

FBal0151405

Feature type

allele

Associated gene

Dmel\stnA

Associated Insertion(s)

Carried in Construct

P{UAS-stnA.E}

Key Links

Transgenic product class

wild_type

(Estes et al., 2003)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Estes et al., 2003)

Mutagen

in vitro construct

(Estes et al., 2003)

Progenitor genotype

Carried in construct

P{UAS-stnA.E}

Cytology

Description

UASt regulatory sequences drive expression of stnA.

(Estes et al., 2003)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

stnA

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

stnA^UAS.cEa, Scer\GAL4^GMR.PF is a suppressor of visible phenotype of Ppt1^UAS.cKa, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Other

Statement

Reference

Scer\GAL4^elav-C155, stnA¹, stnA^UAS.cEa, stnB¹ has lethal phenotype

(Estes et al., 2003)

Scer\GAL4^elav-C155, stnA¹², stnA^UAS.cEa, stnB¹² has lethal phenotype

(Estes et al., 2003)

Scer\GAL4^elav-C155, stnA¹⁵, stnA^UAS.cEa, stnB¹⁵ has lethal phenotype

(Estes et al., 2003)

Phenotype Manifest In

Suppressor of

Statement

Reference

stnA^UAS.cEa, Scer\GAL4^GMR.PF is a suppressor of eye phenotype of Ppt1^UAS.cKa, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Expression of stnA^Scer\UAS.cEa under the control of Scer\GAL4^elav-C155 does not rescue the lethality of stnA¹ stnB¹/Y ("stn^8P1") animals. Expression of stnA^Scer\UAS.cEa under the control of Scer\GAL4^elav-C155 does not rescue the lethality of stnA¹² stnB¹²/Y ("stn^13-120") animals. Expression of stnA^Scer\UAS.cEa under the control of Scer\GAL4^elav-C155 does not rescue the mean excitatory junction potential (EJP) amplitude at the neuromuscular junction in stnA¹⁵ stnB¹⁵ ("stn^C") larvae. Expression of stnA^Scer\UAS.cEa under the control of Scer\GAL4^elav-C155 does not restore the on/off transients in the electroretinograms of stnA¹⁵ stnB¹⁵ ("stn^C") animals.