FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\cnoΔN.UAS
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General Information
Symbol
Dmel\cnoΔN.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0152063
Feature type
allele
Associated gene
Dmel\cno
Associated Insertion(s)
Carried in Construct
P{UAS-cno.ΔN}
Key Links
Transgenic product class
inframe_deletion
(Boettner et al., 2003)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Boettner et al., 2003)
Mutagen
in vitro construct
(Boettner et al., 2003)
Progenitor genotype
Carried in construct
P{UAS-cno.ΔN}
Cytology
Description

UASt regulatory sequences drive expression of an N-terminally truncated form of cno that lacks the RA domains.

(Boettner et al., 2003)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
cno
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Phenotype Manifest In
      NOT Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The overgrowth and increased number of progenitor cells characteristic for cnoR2;scrib1 clones is not significantly suppressed by Scer\GAL4Dll-md23-driven expression of cnoΔN.Scer\UAS in the mutant clones.

      (Rives-Quinto et al., 2017)

      The dorsal closure defects seen in embryos expressing RN17.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4ptc-559.1 are not rescued by co-expression of cnoΔN.Scer\UAS.

      (Boettner et al., 2003)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4ptc-559.1/cnoΔN.UAS partially rescues cno2

      (Boettner et al., 2003)
      Comments

      Expression of cnoΔN.Scer\UAS under the control of Scer\GAL4ptc-559.1 partially rescues the dorsal closure defects of cno2 embryos, although the ability of cnoΔN.Scer\UAS to rescue is strongly reduced compared to the ability of cnoScer\UAS.cBa to rescue; 35% of embryos rescued by cnoΔN.Scer\UAS show a closed cuticle compared to 92% of embryos rescued by cnoScer\UAS.cBa.

      (Boettner et al., 2003)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      cnoΔN.Scer\UAS
      cnoΔN.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)