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General Information
Symbol
Dmel\Tbhhs.PS
Species
D. melanogaster
Name
heat shock construct of Schwaerzel
FlyBase ID
FBal0152162
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
hsp-Tβh
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

An Hsp70 promoter drives expression of a Tbh cDNA.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

3 hours after a 30 minute heat shock to induce expression of Tbhhs.PS, flies have a shortened fighting latency, increased lunging frequency and increased high-intensity fighting (holding, boxing and tussling) compare to control flies when two flies are placed in a small closed chamber containing a food pad at the centre.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescues
Comments

Expression of Tbhhs.PS through heat-shock rescues flight initiation and maintenance in TbhnM18 mutants. No rescue is seen without heat-shock.

TbhnM18 females which are carrying Tbhhs.PS are completely sterile at 18oC and lay a few eggs at 25oC. These females start laying eggs within a few hours of a single heat shock (37oC for 1 hour) and continue to lay eggs for almost 3 days. The rhythmicity of egg laying in the heat shocked females is the same as that of wild-type females. The fertility of these females is 50-60% that of wild type.

Following heat shock, the Tbhhs.PS transgene rescues the sugar memory phenotype of TbhnM18 flies.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Tbhhs.PS
Name Synonyms
heat shock construct of Schwaerzel
Secondary FlyBase IDs
    References (5)