FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\Fas2G0293
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General Information
Symbol
Dmel\Fas2G0293
Species
D. melanogaster
Name
FlyBase ID
FBal0152503
Feature type
allele
Associated gene
Dmel\Fas2
Associated Insertion(s)
P{lacW}Fas2G0293
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Schäfer et al., 1999.6.15)
Progenitor genotype
Associated Insertion(s)
P{lacW}Fas2G0293
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
AJ426667
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Fas2[+]/Fas2G0293 is an enhancer of eye phenotype of rhohs.sev

      (Mao and Freeman, 2009)
      Suppressor of
      Statement
      Reference

      Fas2[+]/Fas2G0293 is a suppressor of eye phenotype of aosGMR.PC

      (Mao and Freeman, 2009)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Fas2e76/Fas2G0293 third instar larvae with GluRIICdsRNA.Scer\UAS.cBa driven by Scer\GAL4C57 do not show impairment of homeostatic compensation at the neuromuscular junction (significant reduction in mEPSP and significant increase in quantal content compared to controls, just as is seen in larvae with expression of GluRIICdsRNA.Scer\UAS.cBa driven by Scer\GAL4C57).

      (Spring et al., 2016)

      rhohs.sev rough eye phenotype is enhanced in the presence of Fas2G0293/+ at 18[o]C.

      argosGMR.PC rough eye phenotype is suppressed in the presence of Fas2G0293/+.

      (Mao and Freeman, 2009)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      Comments
      Comments

      P{lacW} not verified as causing the lethality.

      (Schäfer et al., 1999.6.15)
      External Crossreferences and Linkouts ( 1 )
      Crossreferences
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      Synonyms and Secondary IDs (6)
      Reported As
      Symbol Synonym
      Fas2G0293
      FasIIG0293
      (Spring et al., 2016)
      FasIIG293
      (Spring et al., 2016)
      fas2G0293
      (Mao and Freeman, 2009)
      l(1)G0293
      (Peter et al., 2002)
      l(1)G0293G0293
      (Schäfer et al., 1999.6.15)
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0098123
      References (5)