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General Information
Symbol
Dmel\pumUAS.cYa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Ye
FlyBase ID
FBal0154719
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-pum
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt sequences drive expression of pum cDNA sequences.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of pumScer\UAS.cYa under the control of Scer\GAL4Mhc.PU results in wing posture (age-progressive), jumping ability defects and abnormal mitochondrial morphology in flight muscles in adult flies, while expression under Scer\GAL4ple.PF leads to loss of dopaminergic (DA) neurons from the PPL1 cluster and mitochondrial aggregation in the DA neurons.

Scer\GAL4ppk.PG-mediated overexpression of pumScer\UAS.cYa strongly attenuates C4da terminal dendrite growth in an otherwise wild-type background.

Expression of pumScer\UAS.cYa under the control of Scer\GAL45-78 results in a change in the dendrite morphology of class III dendritic arborization neurons of third instar larvae. Expression of pumScer\UAS.cYa under the control of Scer\GAL4477 results in a change in the dendrite morphology of class IV dendritic arborization neurons of third instar larvae.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT suppressed by
NOT Enhancer of
Phenotype Manifest In
NOT suppressed by
Statement
Reference
NOT Enhancer of
Additional Comments
Genetic Interactions
Statement
Reference

The wing posture and jumping ability defects characteristic for adult flies expressing pumScer\UAS.cYa under the control of Scer\GAL4Mhc.PU are not rescued by co-expression of Pink1Scer\UAS.cYa.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
pumScer\UAS.cYa
pumUAS.cYa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Ye
Secondary FlyBase IDs
    References (4)