FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\endosS067006
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General Information
Symbol
Dmel\endosS067006
Species
D. melanogaster
Name
FlyBase ID
FBal0155325
Feature type
allele
Associated gene
Dmel\endos
Associated Insertion(s)
P{lacW}endosS067006
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Deak et al., 1997)
P-element activity
(Szeged Stock Center, 1998-)
Progenitor genotype
Associated Insertion(s)
P{lacW}endosS067006
Cytology
Description

Insertion in the 5' untranslated region, at position +11 from the predicted start of transcription.

(Drummond-Barbosa and Spradling, 2004)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Hemizygous flies have shrivelled wings, missing thoracic bristles, irregular abdominal bristles, disrupted tergites and legs, and show male and female sterility.

      Hemizygous larval brain neuroblasts have undercondensed mitotic chromosomes and there is a high incidence of chromatin bridges during anaphase.

      (Rangone et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Separable from: a second site independent lethal mutation on the same chromosome.

      (Drummond-Barbosa and Spradling, 2004)
      Comments
      Comments

      The P{lacW}endosS067006 insertion appears to be within the transcription units of both CG6650 and endos (these 2 genes are divergently transcribed).

      (FlyBase, 1996-)

      Precise excision of insertion reverts the mutant phenotype.

      (Rangone et al., 2011)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (8)
      Reported As
      Symbol Synonym
      0670/06
      (Deak et al., 1997)
      dendoss67006
      (Drummond-Barbosa and Spradling, 2004)
      endos670-06
      (Rangone et al., 2011)
      endos67006
      (Rangone et al., 2011)
      endosS067006
      l(3)S067006
      (Szeged Stock Center, 1998-)
      l(3)S067006S067006
      l(3)s67006
      (Drummond-Barbosa and Spradling, 2004)
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0095300
      References (5)