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General Information
Symbol
Dmel\VhaSFDEY04644
Species
D. melanogaster
Name
FlyBase ID
FBal0155711
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Insertion components
P{EPgy2}VhaSFDEY04644
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

VhaSFDEY04644 heterozygotes are viable.

Induction of VhaSFDEY04644 homozygous whole-eye clones in the third instar larva leads to the absence of eyes in adults.

Predominantly mutant VhaSFDEY04644 eye discs (generated using Scer\FLP1ey.PN) are small in size compared to wild type and have aberrant morphology.

VhaSFD[EY04644] eye disc cells show an increased number of multivesicular bodies (MVBs) compared to wild type. These MVBs are enlarged and contain a high number of luminal vesicles.

A portion of the cells in VhaSFDEY04644 mosaic clones are eliminated from the disc, especially when surrounded by wild type cells.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Enhancer of
Statement
Reference
Suppressor of
Statement
Reference

VhaSFDEY04644/VhaSFD[+], Scer\GAL4GMR.PU is a suppressor | partially of visible | heat sensitive phenotype of Ivir\M2UAS.cAa, Scer\GAL4GMR.PU

Other
Phenotype Manifest In
Suppressor of
Statement
Reference

VhaSFDEY04644/VhaSFD[+], Scer\GAL4GMR.PU is a suppressor | partially of eye | heat sensitive phenotype of Ivir\M2UAS.cAa, Scer\GAL4GMR.PU

Additional Comments
Genetic Interactions
Statement
Reference

Expression of rushScer\UAS.T:Avic\GFP under the control of Scer\GAL4arm.PS decreases the fraction of VhaSFDEY04644/+ flies eclosing. This effect is rescued by Df(1)rush4, sta+t4.4.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (8)