FlyBase Allele Report: Dmel\sta[+t4.4]

General Information

Symbol

Dmel\sta^+t4.4

Species

D. melanogaster

Name

FlyBase ID

FBal0035714

Feature type

allele

Associated gene

Dmel\sta

Associated Insertion(s)

Carried in Construct

P{sta⁺}

Key Links

Genomic Maps

JBrowse

Transgenic product class

genomic_DNA

(Melnick et al., 1993)

wild_type

(Melnick et al., 1993)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

genomic_DNA

(Melnick et al., 1993)

wild_type

(Melnick et al., 1993)

Mutagen

in vitro construct

(Melnick et al., 1993)

Progenitor genotype

Carried in construct

P{sta⁺}

Cytology

Description

Contained within a 4.4kb BamHI-EcoRI fragment built from a 3.0kb BamHI-SalI and a 1.4 SalI-EcoRI genomic fragment.

(Melnick et al., 1993)

Allele components

Component

Use(s)

Regulatory region(s)

sta

Encoded product / tool

sta

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

rescue_region

X:1,480,550..1,484,952 [-]

Linked to:

MboI-EcoRI restriction fragment

Comment:

position of restriction fragment on reference sequence inferred by FlyBase curator; the position of the MboI site from which a BamHI site was created may be incorrect

(Melnick et al., 1993)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

wild-type

(Melnick et al., 1993)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Df(1)rush⁴, Rab5², sta^+t4.4 has partially lethal - majority live phenotype, suppressible | partially by rush^UAS.GFP/Scer\GAL4^arm.PS

(Gailite et al., 2012)

Df(1)rush⁴, Hrs^D28, sta^+t4.4 has lethal phenotype, suppressible | partially by rush^UAS.GFP/Scer\GAL4^arm.PS

(Gailite et al., 2012)

Enhancer of

Statement

Reference

sta^+t4.4/Df(1)rush⁴ is an enhancer of lethal | pupal stage phenotype of Hrs^D28

(Gailite et al., 2012)

Suppressor of

Statement

Reference

sta^+t4.4/Df(1)rush⁴ is a suppressor of partially lethal - majority live phenotype of Gdi^AF160, Scer\GAL4^arm.PS, rush^UAS.GFP

(Gailite et al., 2012)

sta^+t4.4/Df(1)rush⁴ is a suppressor of partially lethal - majority live phenotype of Scer\GAL4^arm.PS, car¹, rush^UAS.GFP

(Gailite et al., 2012)

sta^+t4.4/Df(1)rush⁴ is a suppressor of partially lethal - majority live phenotype of Scer\GAL4^arm.PS, VhaSFD^EY04644, rush^UAS.GFP

(Gailite et al., 2012)

Other

Statement

Reference

Df(1)rush⁴, Rab5², sta^+t4.4 has partially lethal - majority live phenotype

(Gailite et al., 2012)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Df(1)rush⁴ flies that also carry sta^+t4.4 are homozygous viable and fertile, demonstrating that rush is an inessential gene.

(Gailite et al., 2012)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

sta^+t4.4 rescues sta¹

(Melnick et al., 1993)

sta^+t4.4 rescues sta²

(Melnick et al., 1993)

Comments

Rescues the lethality of sta² : Rescued flies are viable and fertile. Rescued sta¹ flies have wild type bristles and antennae.

(Melnick et al., 1993)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

sta^+t4.4

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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