FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ToporsAA
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General Information
Symbol
Dmel\ToporsAA
Species
D. melanogaster
Name
FlyBase ID
FBal0155749
Feature type
allele
Associated gene
Dmel\Topors
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Secombe and Parkhurst, 2004)
Progenitor genotype
P{EP}prodEP2435
(Secombe and Parkhurst, 2004)
Caused by aberration
Df(2R)ToporsAA
Cytology
Description

Imprecise excision of the P{EP}prodEP2435 element, resulting in a 4.1kb deletion which removes both prod and Topors sequences (the deletion includes the Topors promoter and translation initiation site).

(Secombe and Parkhurst, 2004)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      ToporsAA mutants (Df(2R)ToporsAA homozygotes in which prod function has been rescued by prod+t5.1) are viable.

      (Secombe and Parkhurst, 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The h26/h30 mutant phenotype is suppressed by ToporsAA/+.

      (Secombe and Parkhurst, 2004)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Df(dtoporsAA)
      (Binder et al., 2025)
      ToporsAA
      dtoporsAA
      (Secombe and Parkhurst, 2004)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)