FlyBase Allele Report: Dmel\Hmt4-20[BG00814]

General Information

Symbol

Dmel\Hmt4-20^BG00814

Species

D. melanogaster

Name

FlyBase ID

FBal0155778

Feature type

allele

Associated gene

Dmel\Hmt4-20

Associated Insertion(s)

P{GT1}Hmt4-20^BG00814

Carried in Construct

Also Known As

Suv4-20^BG00814

Key Links

Genomic Maps

JBrowse

Allele class

hypomorphic allele - genetic evidence

Mutagen

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Schotta et al., 2004)

Mutagen

Progenitor genotype

Associated Insertion(s)

P{GT1}Hmt4-20^BG00814

Cytology

Description

P{GT1} insertion in the third exon.

(Schotta et al., 2004)

Allele components

Component

Use(s)

Inserted element

P{GT1}

gene trap

polyA trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

X:649,492..649,492 [+]

(Phalke et al., 2009, Sakaguchi et al., 2008, Greil et al., 2007, Schotta et al., 2004)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

non-suppressor of variegation

(Sakaguchi et al., 2008)

suppressor of variegation

(Sasai et al., 2007)

suppressor of variegation, with T(2;3)Sb^V

(Neguembor et al., 2013, Schotta et al., 2004)

suppressor of variegation | dominant, with T(2;3)Sb^V

(Greil et al., 2007)

viable

(Schotta et al., 2004)

Phenotype Manifest In

Detailed Description

Statement

Reference

Hmt4-20^BG00814 does not dominantly affect position effect variegation at the Sb locus which is caused by T(2;3)Sb^V.

(Sakaguchi et al., 2008)

Hmt4-20^BG00814 suppresses the position effect variegation of the mutant Sb phenotype which is seen in the T(2;3)Sb^V chromosome.

(Sasai et al., 2007)

Suv4-20^BG00814 homozygotes suppress the variegation of Sb caused by T(2;3)Sb^V, resulting in an increase in the number of adults with a Sb mutant phenotype (short bristles).

(Schotta et al., 2004)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

12510

P{GT1}Hmt4-20^BG00814 w¹¹¹⁸

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Hmt4-20^BG00814

SUV4-20^BG00814

(Sasai et al., 2007)

Suv4-20^BG00814

(Neguembor et al., 2013, Phalke et al., 2009)

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

Open Close