FlyBase Allele Report: Dmel\Mef2[26-49]

General Information

Symbol

Dmel\Mef2^26-49

Species

D. melanogaster

Name

FlyBase ID

FBal0156256

Feature type

allele

Associated gene

Dmel\Mef2

Associated Insertion(s)

Carried in Construct

Also Known As

26-49

Key Links

Genomic Maps

JBrowse

Allele class

hypomorphic allele - genetic evidence

Mutagen

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Lovato et al., 2009)

Mutagen

ethyl methanesulfonate

(Goldstein et al., 2001)

diepoxybutane

(Goldstein et al., 2001)

gamma ray

(Goldstein et al., 2001)

Progenitor genotype

Cytology

Description

Amino acid replacement: T148A.

(Lovato et al., 2009)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

point_mutation

2R:9,919,564..9,919,564 [-]

Nucleotide change:

A9919564G

Reported nucleotide change:

A?G

Amino acid change:

Reported amino acid change:

T148A

(Lovato et al., 2009)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal (with Df(2R)X1)

(Goldstein et al., 2001)

lethal (with Mef2^22-21)

(Baker et al., 2005)

lethal (with Mef2^22-24)

(Baker et al., 2005)

lethal (with Mef2^25-42)

(Baker et al., 2005)

lethal (with Mef2^26-6)

(Baker et al., 2005)

lethal (with Mef2^26-7)

(Baker et al., 2005)

lethal (with Mef2^48-7)

(Baker et al., 2005)

lethal (with Mef2^66-25)

(Baker et al., 2005)

lethal | recessive

(Baker et al., 2005)

partially lethal (with Mef2^25-34)

(Baker et al., 2005)

partially lethal (with Mef2^30-5)

(Baker et al., 2005)

partially lethal (with Mef2^44-5)

(Baker et al., 2005)

partially lethal (with Mef2^55-5)

(Baker et al., 2005)

partially lethal (with Mef2^78-11)

(Baker et al., 2005)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially complements

Mef2^25-34

(Baker et al., 2005)

Mef2^30-5

(Baker et al., 2005)

Mef2^44-5

(Baker et al., 2005)

Mef2^55-5

(Baker et al., 2005)

Mef2^78-11

(Baker et al., 2005)

Fails to complement

Mef2^22-24

(Baker et al., 2005)

Mef2^25-42

(Baker et al., 2005)

Mef2^26-6

(Baker et al., 2005)

Mef2^26-7

(Baker et al., 2005)

Mef2^48-7

(Baker et al., 2005)

Mef2^22-21

(Baker et al., 2005)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

"ethyl methanesulfonate" was stated as tentative. "diepoxybutane" was stated as tentative. "γ ray" was stated as tentative.

(Goldstein et al., 2001)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

26-49

(Lovato et al., 2009, Goldstein et al., 2001)

Mef2^26-49

mef2^26-49

(Crittenden et al., 2018)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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