FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Kap3V5
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General Information
Symbol
Dmel\Kap3V5
Species
D. melanogaster
Name
FlyBase ID
FBal0156306
Feature type
allele
Associated gene
Dmel\Kap3
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Sarpal et al., 2003)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutant adults show no electroantennogram response to a number of odorants.

      (Jana et al., 2011)

      Homozygotes do not emerge from the pupal case. However if they are rescued from the pupal case some survive for 2-4 days. These mutants are uncoordinated; they cannot stand or right themselves when turned on their back, and their legs get entangled in an attempt to walk. Electroretinogram responses are normal.

      (Sarpal et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      NOT suppressed by
      Statement
      Reference

      Kap3V5 has abnormal neurophysiology phenotype, non-suppressible by Klp68DUAS.YFP/Scer\GAL4ChAT.7.4

      (Jana et al., 2011)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Klp64DScer\UAS.T:Avic\GFP under the control of Scer\GAL4Cha.7.4 partially restores cilia growth in the sensilla basiconica and sensilla trichodea of the antennae in Kap3V5 adults (cilia length is restored almost to wild type, while cilia volume is restored to approximately 25% of the normal level). Odor-evoked electroantennogram responses are also partly restored in these animals (assayed in response to ethyl acetate, n-butanol, benzaldehyde and propionic acid).

      Expression of Klp68DScer\UAS.T:Avic\GFP-YFP under the control of Scer\GAL4Cha.7.4 does not rescue odor-evoked electroantennogram responses in Kap3V5 adults.

      (Jana et al., 2011)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Kap3V5 is rescued by Kap3+t12

      (Jana et al., 2011)

      Kap3V5 is rescued by Kap3+t20

      (Jana et al., 2011)

      Kap3V5/Kap3V6 is rescued by Scer\GAL4SG18.1/Kap3UAS.cSa

      (Sarpal et al., 2003)

      Kap3V5/Kap3V6 is rescued by Scer\GAL4elav-C155/Kap3UAS.cSa

      (Sarpal et al., 2003)
      Comments

      Kap3+t12 and Kap3+t20 rescue the odor-evoked electroantennogram response in Kap3V5 animals (assayed in response to ethyl acetate, n-butanol, benzaldehyde and propionic acid).

      (Jana et al., 2011)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      DmKap3V5
      (Sarpal et al., 2003)
      DmKapv5
      (Jana et al., 2011)
      Kap3V5
      Name Synonyms
      Secondary FlyBase IDs
        References (2)