FB2026_02 , released June 18, 2026
Allele: Dmel\Pcyt1179
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General Information
Symbol
Dmel\Pcyt1179
Species
D. melanogaster
Name
FlyBase ID
FBal0156792
Feature type
allele
Associated gene
Dmel\Pcyt1
Associated Insertion(s)
Carried in Construct
Also Known As
CCT1179
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Gupta and Schupbach, 2003, Weber et al., 2003)
Mutagen
Delta2-3 transposase
(Gupta and Schupbach, 2003)
Progenitor genotype
Pcyt1BN81
(Gupta and Schupbach, 2003)
Cytology
Description

Imprecise excision has created a deletion. The first (untranslated) exons of all transcripts have been removed along with the beginning of the translated exon 2, including the start codon.

(Gupta and Schupbach, 2003)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      When homozygous mutant clones are made in apical cells of the developing ovariole, no migration defects are seen. Homozygous mutant germ-line clones do not give a loss of female germline stem cell phenotype. No mis-positioning of the oocyte is seen in these animals either When somatic clones are made in the follicle cells, no mis-positioning of the oocyte is seen.

      (Gupta and Schupbach, 2003)

      Cct1179 mitotic clone cells initially develop normally with no obvious defects in cellular architecture. Cct1179 clones in third larval instar eye discs show defects in tissue polarity due to aberrant ommatidial rotation. There are also defects in cell fate selection of the R3/R4 photoreceptor pair leading to abnormal ommatidial chirality. In Cct1179 mutant photoreceptor clones, rhabdomeres fail to form properly.

      (Weber et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhancer of
      Statement
      Reference

      Pcyt1[+]/Pcyt1179 is a non-enhancer of decreased cell number | somatic clone | progressive phenotype of Pect29, Scer\FLP1ey.PU

      (Zhao and Wang, 2020)
      NOT Suppressor of
      Statement
      Reference

      Pcyt1[+]/Pcyt1179 is a non-suppressor of decreased cell number | somatic clone | progressive phenotype of Pect29, Scer\FLP1ey.PU

      (Zhao and Wang, 2020)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Cct1[+]/Pcyt1179 is an enhancer of wing phenotype of N55e11

      (Weber et al., 2003)
      NOT Enhancer of
      Statement
      Reference

      Pcyt1[+]/Pcyt1179 is a non-enhancer of eye photoreceptor cell | somatic clone | decreased number phenotype of Pect29, Scer\FLP1ey.PU

      (Zhao and Wang, 2020)

      Pcyt1[+]/Pcyt1179 is a non-enhancer of rhabdomere | somatic clone | decreased number phenotype of Pect29, Scer\FLP1ey.PU

      (Zhao and Wang, 2020)
      NOT Suppressor of
      Statement
      Reference

      Pcyt1[+]/Pcyt1179 is a non-suppressor of eye photoreceptor cell | somatic clone | decreased number phenotype of Pect29, Scer\FLP1ey.PU

      (Zhao and Wang, 2020)

      Pcyt1[+]/Pcyt1179 is a non-suppressor of rhabdomere | somatic clone | decreased number phenotype of Pect29, Scer\FLP1ey.PU

      (Zhao and Wang, 2020)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The Cct1179 allele dominantly enhances the notched wing phenotype seen in N55e11/+ flies.

      (Weber et al., 2003)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      CCT1179
      (Haider et al., 2018, Weber et al., 2003)
      Cct1179
      Pcyt1179
      (Zhao and Wang, 2020)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)