FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ytrΔP22
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General Information
Symbol
Dmel\ytrΔP22
Species
D. melanogaster
Name
FlyBase ID
FBal0158447
Feature type
allele
Associated gene
Dmel\ytr
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Sinenko et al., 2004)
Progenitor genotype
ytrk13108
(Sinenko et al., 2004)
Cytology
Description

Imprecise excision of the P{lacW} transposon has created a deletion that disrupts the ytr gene.

(Sinenko et al., 2004)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous larvae show an increase in the number of hemocytes compared to control larvae.

      (Sinenko and Mathey-Prevot, 2004)

      Mutant animals exhibit a marked enlargement of the first lobes of the lymph gland, which occasionally contain melanised hemocytes. In addition hemocytes are larger and more heterogeneous in size and shape than those found in wild-type. The proportion of lamellocytes is greatly increased compared to wild-type. Many of the larger rounder hemocytes in the lymph glands and in circulation (up to 10% of all hemocytes) contain two nuclei.

      (Sinenko et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The increased number of hemocytes that is seen in ytrΔP22 homozygous larvae is suppressed by Tsp68C+t3.0, but is not suppressed by Tsp68Cstop.

      (Sinenko and Mathey-Prevot, 2004)
      Xenogenetic Interactions
      Statement
      Reference

      Expression of Mmus\ytrScer\UAS.cSa under the control of Scer\GAL4stop.Hml rescues the increased number of hemocytes that is seen in ytrΔP22 homozygous larvae.

      (Sinenko and Mathey-Prevot, 2004)
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ytrΔP22
      (Sinenko and Mathey-Prevot, 2004)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)