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General Information
Symbol
Dmel\mip1301-36
Species
D. melanogaster
Name
FlyBase ID
FBal0158949
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Mutation in mip130 resulting in a new BamHI site 45 nucleotides from the start codon. The mutant allele is expected to produce a 36 amino acid protein, of which the last 21 amino acids are not mip130 sequence.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Embryos derived from females carrying homozygous mip1301-36 germline clones crossed to wild type males are able to hatch at a similar rate to wild type.

Mutant animals are smaller than wild-type and are unhealthy. Mutant females produce eggs that are flaccid and have thin eggshells. Very few larvae hatch.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT Enhanced by
Statement
Reference

mip1301-36 has female semi-sterile phenotype, non-enhanceable by MybMH107

NOT suppressed by
Statement
Reference

mip1301-36 has female semi-sterile phenotype, non-suppressible by MybMH107

Suppressor of
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Homozygous mip1301-36 suppresses the eye phenotypes seen in lin-5293 mutant eye clones. The mutant tissue appears completely normal.

Homozygous mip1301-36 suppresses the eye phenotypes seen in MybMH107, lin-5293 double mutant clones. The resulting triple mutant eyes appear completely normal.

Approximately 29% of embryos derived from females carrying homozygous lin-5293 mip1301-36 double mutant germline clones crossed to wild type males are able to hatch, a partial suppression of the phenotype seen when females are maternally mutant for lin-5293 alone.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (5)