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General Information
Symbol
Dmel\Tsc1f01910
Species
D. melanogaster
Name
FlyBase ID
FBal0159590
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Insertion components
PBac{WH}Tsc1f01910
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Suppressed by
Statement
Reference
Enhancer of
Statement
Reference
Phenotype Manifest In
Enhanced by
Statement
Reference
Suppressed by
Statement
Reference
Enhancer of
Additional Comments
Genetic Interactions
Statement
Reference

Generating Tsc1f01910 clones in Rbf120a eye discs produce an increase in the level of ectopic cell death.

Tsc1f01910 E2frM729 double mutant eye disc clones in a wild-type background are smaller than Tsc1f01910 single mutant eye disc clones.

When Tsc1f01910 E2frM729 double mutant clones are generated in Rbf120a, the sizes of the Tsc1f01910 E2frM729 double mutant clones are much smaller than that of Tsc1f01910 single mutant clones.

The prevailing cell death phenotype observed in Rbf120a Tsc1f01910 double mutant clones at the morphogenetic furrow is no longer present in Rbf120a E2frM729 Tsc1f01910 triple mutant cells, indicating that the increased level of ectopic cell death observed in Rbf120a Tsc1f01910 double mutant cells is E2f-dependent.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Tsc1f01910
tsc1f01910
Name Synonyms
Secondary FlyBase IDs
    References (4)