FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Dap160UAS.cKa
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General Information
Symbol
Dmel\Dap160UAS.cKa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Koh
FlyBase ID
FBal0160625
Feature type
allele
Associated gene
Dmel\Dap160
Associated Insertion(s)
Carried in Construct
P{UAS-Dap160.K}
Key Links
Transgenic product class
genomic_DNA
(Koh et al., 2004)
wild_type
(Koh et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Koh et al., 2004)
wild_type
(Koh et al., 2004)
Mutagen
in vitro construct
(Koh et al., 2004)
Progenitor genotype
Carried in construct
P{UAS-Dap160.K}
Cytology
Description

UAS regulatory sequences drive expression of a genomic fragment of Dap160 which spans from the TATA box to the last exon.

(Koh et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Dap160
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  Parkinson's disease 1
      modeled by Hsap\SNCAUAS.cJa
      (Spargo et al., 2025)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Dap160Scer\UAS.cKa in photoreceptors under the control of Scer\GAL4GMR.PF produces electroretinogram depolarisation amplitudes that are similar to controls.

      (Scappini et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of Dap160Scer\UAS.cKa suppresses the increase in the total number of boutons and in the number of satellite boutons at the neuromuscular junction that is seen in larvae expressing two copies of tkvQ199D.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4elav-C155.

      Expression of Dap160Scer\UAS.cKa under the control of Scer\GAL4elav-C155 suppresses the increase in the total number of boutons and in the number of satellite boutons at the neuromuscular junction that is seen in homozygous Dadj1E4 larvae.

      (O'Connor-Giles et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference

      Co-expression of Dap160Scer\UAS.cKa enhances the reduction in electroretinogram depolarisation amplitude seen when Zzzz\CAGQ48.Scer\UAS.T:Hsap\MYC,T:Zzzz\FLAG is expressed in photoreceptors under the control of Scer\GAL4GMR.PF.

      (Scappini et al., 2007)
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Dap160Scer\UAS.cKa
      Dap160UAS.cKa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Koh
      (Koh et al., 2004)
      Secondary FlyBase IDs
        References (5)