FlyBase Allele Report: Dmel\AstC-R2[f03116]

General Information

Symbol

Dmel\AstC-R2^f03116

Species

D. melanogaster

Name

FlyBase ID

FBal0162821

Feature type

allele

Associated gene

Dmel\AstC-R2

Associated Insertion(s)

PBac{WH}AstC-R2^f03116

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

piggyBac activity

Nature of the Allele

Allele class

Mutagen

piggyBac activity

(Bloomington Drosophila Stock Center, 2004.11.6)

Progenitor genotype

Associated Insertion(s)

PBac{WH}AstC-R2^f03116

Cytology

Description

Allele components

Component

Use(s)

Inserted element

PBac{WH}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Also carries

FRT

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3L:18,488,606..18,488,606 [+]

(Liu et al., 2023, Bloomington Drosophila Stock Center, 2004.11.6)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

fertile

(Bloomington Drosophila Stock Center, 2004.11.6)

viable

(Bloomington Drosophila Stock Center, 2004.11.6)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

AstC-R2[+]/AstC-R2^f03116 is an enhancer of partially lethal - majority live phenotype of ct^A, lncRNA:flam^A

(Guida et al., 2016)

Other

Statement

Reference

AstC-R2^f03116, ct[+]/ct^A, lncRNA:flam^A has partially lethal - majority live phenotype

(Guida et al., 2016)

AstC-R2^f03116, ct^A, lncRNA:flam^A has lethal - all die before end of P-stage phenotype

(Guida et al., 2016)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

flam^A, AstC-R2^f03116 double homozygotes also heterozygous for ct^A, but not flam^A homozygotes that are also heterozygous or homozygous for AstC-R2^f03116, display significant mortality during the pharate stage.

flam^A, ct^A double homozygotes display significant mortality during the pharate stage as compared to controls, which is significantly increased or even reaches lethality by AstC-R2^f03116 heterozygosity or homozygosity, respectively; these flam^A, ct^A, AstC-R2^f03116 triple homozygous lethal pharates become trapped in the pupal case, still exhibiting pupal membrane attached several body parts.

(Guida et al., 2016)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

18622

w¹¹¹⁸; PBac{WH}AstC-R2^f03116/TM6B, Tb⁺

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

AlCR2^f03116

AstC-R2^f01336

(Liu et al., 2023)

AstC-R2^f03116

(Guida et al., 2016)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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