flam^A/flam^A, AstC-R2^f03116/AstC-R2^f03116, ct^A/+ mutants display significant mortality during the pharate stage, but not flam^A/flam^A, AstC-R2^f03116/+ or flam^A/flam^A, AstC-R2^f03116/AstC-R2^f03116 mutants.

flam^A, ct^A double homozygotes display significant mortality during the pharate stage as compared to controls, which is significantly increased or even reaches lethality by AstC-R2^f03116 heterozygosity or homozygosity, respectively; these flam^A, ct^A, AstC-R2^f03116 triple homozygous lethal pharates become trapped in the pupal case, still exhibiting pupal membrane attached to several body parts; the mortality of flam^A, ct^A double homozygotes is partially suppressed by heterozygosity for either Su(var)205⁵, Su(var)3-9², AGO2⁴¹⁴, Dcr-2^L811fsX, AGO3^t2 or aub^HN2, fully suppressed by either Su(var)3-7^DG10405, Su(var)3-9¹, or AGO2⁴¹⁴, AGO3^t2 double heterozygosity; flam^A/flam¹, ct^A/ct⁶ double transheterozygotes show a small but significant increase in mortality as compared to flam^A/flam¹ single heterozygotes.

flam^A/flam^A, ct^A/+,f^A/+ mutants, but not flam^A/flam^A, f^A/f^A mutants, exhibit a small but significant increase in pharate mortality, as compared to controls.