The co-expression of both spdoScer\UAS.cOa and Rbfox1dsRNA.Scer\UAS under the control of Scer\GAL4sca-109-68 strongly enhances the supernumerary thoracic sensory bristle phenotype observed upon the expression of either spdoScer\UAS.cOa alone or Rbfox1dsRNA.Scer\UAS alone, and even leads to an increase in the number of other (i.e. non-bristle) sensory organs in the thorax, as compared to controls.
Simultaneously expressing spdoScer\UAS.cOa under the control of Scer\GAL4nub-AC-62 in a Df(1)N-81k1/+ and numb2/+ background partially suppresses wing notching, vein thickening, and reduced wing size observed in the absence of numb2.
Expression of spdoScer\UAS.cOa under the control of Scer\GAL4twi.PG in the presence of numb2/+ suppresses the formation of extra svp-positive heart precursors by stage 12, and extra progenitor svp-positive pericardial cells, to almost wildtype levels.
Expression of spdoScer\UAS.cOa under the control of Scer\GAL4twi.PG in a numb2 mutant embryo blocks the formation of svp-positive precursor cells, resulting in dramatically fewer svp-positive heart cells and less cardioblasts. Fewer svp-negative cardioblasts develop.
eve-positive equivalence groups form but less eve-positive pericardial cells are seen compared to wildtype when spdoScer\UAS.cOa is expressed under the control of Scer\GAL4twi.PG in a numb2 background.
eve-positive equivalence groups form normally in numb2 mutant embryos that express spdoScer\UAS.cOa under the control of Scer\GAL4twi.PG. However, eve-positive precursors fail to segregate from approximately half of the equivalence groups, resulting in the formation of far fewer eve-positive pericardial cells than in numb2 mutant embryos.