FB2026_02 , released June 18, 2026
Allele: Dmel\snRNP-U1-70K::HsapSRSF1HCterm
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General Information
Symbol
Dmel\snRNP-U1-70K::Hsap\SRSF1HCterm
Species
D. melanogaster
Name
FlyBase ID
FBal0175471
Feature type
allele
Associated gene
snRNP-U1-70K::Hsap\SRSF1
Associated Insertion(s)
Carried in Construct
P{snRNP70K::Hsap\SFRS1HCterm}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Salz et al., 2004)
Progenitor genotype
snRNP-U1-70K+t9
(Salz et al., 2004)
Carried in construct
P{snRNP70K::Hsap\SFRS1HCterm}
Cytology
Description

The sequence encoding the snRNP-U1-70K C-terminal domain (amino acids 353-448) has been replaced by sequences encoding the C-terminal domain of Hsap\SRSF1 (amino acids 395-437).

(Salz et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
snRNP-U1-70K
Encoded product / tool
snRNP-U1-70K::Hsap\SRSF1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      snRNP-U1-70K::Hsap\SRSF1HCterm is a suppressor of lethal phenotype of snRNP-U1-70K2/snRNP-U1-70KON35

      (Salz et al., 2004)
      Other
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      snf148 has no significant effect on the survival rate of snRNP70KON35/snRNP70K2 ; snRNP70K::Hsap\SFRS1HCterm adults.

      (Salz et al., 2004)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      snRNP-U1-70K::Hsap\SFRS1HCterm
      snRNP-U1-70K::Hsap\SRSF1HCterm
      snRNP70K::Hsap\SFRS1HCterm
      Name Synonyms
      Secondary FlyBase IDs
        References (1)