FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\scyl113
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General Information
Symbol
Dmel\scyl113
Species
D. melanogaster
Name
FlyBase ID
FBal0175522
Feature type
allele
Associated gene
Dmel\scyl
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Reiling and Hafen, 2004)
Progenitor genotype
scylEP9.85
(Reiling and Hafen, 2004)
Cytology
Description

Imprecise excision of the double headed "EP" element, resulting in a deletion of scyl sequences.

(Reiling and Hafen, 2004)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      scyl31/scyl113 is an enhancer of eye phenotype of AktUAS.cRa, Pdk1UAS.cRa, Scer\GAL4GMR.PF

      (Reiling and Hafen, 2004)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      scyl113 chrb180/Df(3L)vin4 double mutant flies have increased body weight compared to control flies. Cells in scyl113 chrb180 double mutant clones in the eye are slightly enlarged compared to wild type. scyl113 chrb180 double homozygotes are sensitive to hypoxia; double homozygotes show reduced survival to adulthood under hypoxic conditions compared to normoxic conditions. The large eye phenotype caused by co-expression of Akt1Scer\UAS.cRa and Pk61CScer\UAS.cRa under the control of Scer\GAL4GMR.PF is enhanced if the flies also carry scyl31/scyl113.

      (Reiling and Hafen, 2004)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      scy113
      (Reiling and Hafen, 2004)
      scyl113
      Name Synonyms
      Secondary FlyBase IDs
        References (1)