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General Information
Symbol
Dmel\edlUAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0175691
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-MAE
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of edl tagged with Tag:MYC.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Flies expressing edlScer\UAS.T:Hsap\MYC under the control of Scer\GAL4tsh-md621 have notum defects and small, malformed wings.

Flies expressing edlScer\UAS.T:Hsap\MYC under the control of Scer\GAL4hs.2sev have wild-type eyes. Expression of edlScer\UAS.T:Hsap\MYC under the control of Scer\GAL4GMR.PF results in gross disorganisation of the external morphology of the adult eye. Eye imaginal discs show increased cell death posterior to the morphogenetic furrow in third instar larvae expressing edlScer\UAS.T:Hsap\MYC under the control of Scer\GAL4GMR.PF.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

The rough eye phenotype caused by aopACT.sev is enhanced by expression of edlScer\UAS.T:Hsap\MYC under the control of Scer\GAL4hs.2sev. Co-expression of pntP2.Scer\UAS.T:Zzzz\FLAG completely rescues the severe rough eye phenotype caused by expression of edlScer\UAS.T:Hsap\MYC under the control of Scer\GAL4GMR.PF, restores the normal recruitment of photoreceptors and cone cells and reduces cell death to wild-type levels.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
edlScer\UAS.T:Hsap\MYC
edlUAS.Tag:MYC
Name Synonyms
Secondary FlyBase IDs
    References (2)