FlyBase Allele Report: Dmel\dlt[A1]

General Information

Symbol

Dmel\dlt^A1

Species

D. melanogaster

Name

FlyBase ID

FBal0180184

Feature type

allele

Associated gene

Dmel\dlt

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Pielage et al., 2003)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal size | adult stage

(Pielage et al., 2003)

abnormal size | adult stage | somatic clone

(Pielage et al., 2003)

lethal - all die before end of pupal stage

(Pielage et al., 2003)

lethal - all die before end of pupal stage (with Df(3L)Aprt-32)

(Pielage et al., 2003)

some die during pupal stage

(Pielage et al., 2003)

some die during pupal stage (with Df(3L)Aprt-32)

(Pielage et al., 2003)

Phenotype Manifest In

antenna

(Pielage et al., 2003)

eye

(Pielage et al., 2003)

eye | somatic clone

(Pielage et al., 2003)

eye-antennal disc

(Pielage et al., 2003)

Detailed Description

Statement

Reference

dlt^A1 mutant eye discs are very small and lack the antennal part. dlt^A1 mutant eyes, generated using the Minute technique, can be significantly smaller than wild-type eyes, although this phenotype is extremely variable. BrdU incorporation is still able to occur during eye development, indicating that DNA synthesis during proliferation is not affected.

(Pielage et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions