dltdre1 mutant eyes, generated using the Minute technique, can be significantly smaller than wild-type eyes, although this phenotype is extremely variable. BrdU incorporation is still able to occur during eye development, indicating that DNA synthesis during proliferation is not affected. dltdre1 cell clones in the eye imaginal disc generated using the FLP/FRT technique are of a similar size to wild-type cells, but these clones can never survive to be found in the adult compound eye. dltdre1 FLP/FRT cell clones are also of a similar size to wild-type cells when induced in the wing disc.
Homozygous follicle cell clones induced before formation of the follicular epithelium show gaps of variable size in the epithelium.