UAS regulatory sequences drive expression of the Rab5 ORF, tagged at the N-terminal end with EGFP.
Adults expressing Rab5UAS.EGFP under the control of Scer\GAL4elav.PLu do not exhibit climbing defects compared to controls.
Animals expressing Rab5Scer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4ptc-559.1 do not show trichome polarity defects in the wings.
Rab5Scer\UAS.T:Avic\GFP-EGFP, under the regulation of Scer\GAL4elav-C155 does not significantly alter the synaptic area, nor the active zone density of presynaptic terminals, implying that the total number of active zones is normal.
Rab5UAS.EGFP, Scer\GAL4elav.Switch.PO is an enhancer of short lived | RU486 conditional phenotype of Hsap\APP2xAPP.SP.UAS, Scer\GAL4elav.Switch.PO
Rab5UAS.EGFP, Scer\GAL4elav.PLu is a non-enhancer of abnormal locomotor behavior | adult stage | progressive phenotype of Scer\GAL4elav.PLu, SgshGD1578
Rab5UAS.EGFP, Scer\GAL4elav.Switch.PO is a non-suppressor of abnormal locomotor behavior | RU486 conditional phenotype of Hsap\APP2xAPP.SP.UAS, Scer\GAL4elav.Switch.PO
BacA\p35UAS.cHa, Rab5UAS.EGFP, Scer\GAL4ptc-559.1 has abnormal planar polarity phenotype
Scer\GAL4GMR.PF/Rab5UAS.EGFP is a suppressor of rhabdomere of eye photoreceptor cell phenotype of Hsap\HTTGMR.Q120
BacA\p35UAS.cHa, Rab5UAS.EGFP, Scer\GAL4ptc-559.1 has wing hair phenotype
Animals co-expressing BacA\p35Scer\UAS.cHa and Rab5Scer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4ptc-559.1 show planar polarity defects in the wing.
Scer\GAL4ppk.PU/Rab5UAS.EGFP rescues Rab5S43N.UAS
Scer\GAL4elav-C155/Rab5UAS.EGFP rescues Rab5k08232
The Rab5k08232 lethality and phenotype are caused by reduced Rab5 levels in the nervous system as they can be rescued by restricted expression of Rab5Scer\UAS.T:Avic\GFP-EGFP, under the regulation of Scer\GAL4elav-C155 in the nervous system.