FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Dscam1exon17.1.UAS.GFP
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General Information
Symbol
Dmel\Dscam1exon17.1.UAS.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0189566
Feature type
allele
Associated gene
Dmel\Dscam1
Associated Insertion(s)
Carried in Construct
P{UAS-Dscam1.exon17.1.GFP}
Also Known As
UAS-Dscam::GFP, UAS-Dscam17.1::GFP, UAS-Dscam17.1-GFP, UAS-Dscam[TM1]::GFP
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Zheng et al., 2006, Wang et al., 2004)
Progenitor genotype
Carried in construct
P{UAS-Dscam1.exon17.1.GFP}
Cytology
Description

UAS regulatory sequences drive expression of Dscam1 which is tagged at the C-terminal end with GFP. The Dscam1 sequences contain the 17.1 alternative exon.

(Wang et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Dscam1
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      DL1 olfactory projection neuron clones expressing Dscam1exon17.1.Scer\UAS.T:Avic\GFP under the control of Scer\GAL4GH146 exhibit ectopic dendrite arborization and loss of the dorsal branch in the lateral horn.

      (Okumura et al., 2015)

      Overexpression of Dscam1exon17.1.Scer\UAS.T:Avic\GFP in da neurons, under the control of Scer\GAL4ppk.PG results in a 24% increase in presynaptic growth.

      (Kim et al., 2013)

      Mushroom body gross morphology appears normal in animals expressing Dscamexon17.1.Scer\UAS.T:Avic\GFP under the control of Scer\GAL4OK107. However, the mushroom body calyx is reduced in size.

      (Wang et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      Scer\GAL4ey-OK107/Dscam1exon17.1.UAS.GFP fails to rescue Dscam1RNAi.UAS.18

      (Shi et al., 2007)
      Comments

      Co-expression of Dscamexon17.1.Scer\UAS.T:Avic\GFP fails to rescue the mushroom body phenotype of DscammiRNA.Scer\UAS.18 Scer\GAL4ey-OK107 animals.

      (Shi et al., 2007)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      FlyBase curator comment: Dscamexon17.1.Scer\UAS.T:Avic\GFP is used to record information in FlyBase when authors use one of the following alternative exon 17.1 containing UAS-Dscam-GFP constructs described in FBrf0180573, but do not specify which one was used; DscamA-17.1+19+23.Scer\UAS.T:Avic\GFP, DscamA-17.1+19-23.Scer\UAS.T:Avic\GFP, DscamA-17.1-19+23.Scer\UAS.T:Avic\GFP, DscamA-17.1-19-23.Scer\UAS.T:Avic\GFP, DscamB-17.1+19+23.Scer\UAS.T:Avic\GFP, DscamB-17.1+19-23.Scer\UAS.T:Avic\GFP.

      (Wang et al., 2004)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Dscam1exon17.1.Scer\UAS.T:Avic\GFP
      Dscam1exon17.1.UAS.GFP
      Dscamexon17.1.Scer\UAS.T:Avic\GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (32)