FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\dmt589
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General Information
Symbol
Dmel\dmt589
Species
D. melanogaster
Name
FlyBase ID
FBal0191158
Feature type
allele
Associated gene
Dmel\dmt
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Myat et al., 2005)
Progenitor genotype
Cytology
Description

Amino acid replacement: Q326term.

(Kerman and Andrew, 2010)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:9,712,244..9,712,244 [+]
Nucleotide change:

C9712244T

Amino acid change:

Q326term | dmt-PA

Reported amino acid change:

Q326term

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Kerman and Andrew, 2010)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous dmt589 mutant embryos exhibit frequent breaks and/or gaps in the dorsal trunk, often associated with shorter ventral tracheal branches. Individual salivary ducts often have significant gaps or are completely missing.

      dmt589/dmt3999 mutant embryos exhibit frequent breaks and/or gaps in the dorsal trunk, often associated with shorter ventral tracheal branches. Individual salivary ducts often have significant gaps or are completely missing.

      dmt589/dmtI184 mutant embryos exhibit frequent breaks and/or gaps in the dorsal trunk, often associated with shorter ventral tracheal branches. Individual salivary ducts often have significant gaps or are completely missing.

      dmt589/Df(3R)GB104 mutant embryos exhibit frequent breaks and/or gaps in the dorsal trunk, often associated with shorter ventral tracheal branches. Individual salivary ducts often have significant gaps or are completely missing.

      (Kerman and Andrew, 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      dmt3999

      (Myat et al., 2005)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Selected as: a mutation that disrupts tracheal development when homozygous.

      (Myat et al., 2005)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      aul589
      dmt589
      Name Synonyms
      Secondary FlyBase IDs
        References (2)