FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\nvyRNAi.UAS
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General Information
Symbol
Dmel\nvyRNAi.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0191192
Feature type
allele
Associated gene
Dmel\nvy
Associated Insertion(s)
Carried in Construct
P{UAS-nvy.RNAi}
Key Links
Transgenic product class
RNAi_reagent
(Wildonger and Mann, 2005)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Wildonger and Mann, 2005)
Mutagen
in vitro construct
(Wildonger and Mann, 2005)
Progenitor genotype
Carried in construct
P{UAS-nvy.RNAi}
Cytology
Description

UASt sequences drive expression of cDNA nvy sequences (nucleotides 1314-1889), fused to an inverted complimentary genomic fragment corresponding to the same region.

(Wildonger and Mann, 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
nvy
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Removing nvy makes cells less likely to adopt sensory organ precursor fate as there are significantly more sensory organ precursors along the outside border of clones expressing nvydsRNA.Scer\UAS under the control of Scer\GAL4αTub84B.PZ generated in wing discs, than there are along the inside borders of the clone.

      (Wildonger and Mann, 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Inhibition of nvy expression, achieved by expressing nvydsRNA.Scer\UAS under the control of Scer\GAL4pnr-MD237, enhances the extra bristle phenotype of Scer\GAL4pnr-MD237 > daScer\UAS.cGa flies.

      (Wildonger and Mann, 2005)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Transfected into flies to study the phenotypic consequences of dsRNA interference (RNAi) of the nvy gene.

      (Wildonger and Mann, 2005)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      nvyRNAi.UAS
      nvydsRNA.Scer\UAS
      nvydsRNA.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)