FB2026_03 , released September 17, 2026
Allele: Dmel\bw16
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General Information
Symbol
Dmel\bw16
Species
D. melanogaster
Name
FlyBase ID
FBal0191564
Feature type
allele
Associated gene
Dmel\bw
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Kondrashov et al., 2006.2.14)
Progenitor genotype
Cytology
Description

Amino acid replacement: A78V. Nucleotide substitution: C?T. CTGGCGGCGATTTCG > CTGGCGGTGATTTCG.

(Kondrashov et al., 2006.2.14)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2R:23,537,918..23,537,918 [-]
Nucleotide change:

C23537918T

Reported nucleotide change:

C?T

Amino acid change:

A78V | bw-PA; A78V | bw-PD

Reported amino acid change:

A78V

(Kondrashov et al., 2006.2.14)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhancer of
      Statement
      Reference

      bw16/bw[+] is a non-enhancer of chemical sensitive phenotype of Gk1RNAi.UAS, Scer\GAL4c564

      (Wightman et al., 2012)
      NOT Suppressor of
      Statement
      Reference

      bw16/bw[+] is a non-suppressor of chemical sensitive phenotype of Gk1RNAi.UAS, Scer\GAL4c564

      (Wightman et al., 2012)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The glycerol hypersensitivity of flies expressing GykdsRNA.Scer\UAS under the control of Scer\GAL4c564 (seen as a reduction in survival on a glycerol only food source) is not significantly affected if the flies are heterozygous for bw16.

      (Wightman et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      bw16
      (Wightman et al., 2012, Ambegaokar and Jackson, 2011, Ambegaokar and Jackson, 2010)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)