FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Liprin-αUAS.Tag:HA
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General Information
Symbol
Dmel\Liprin-αUAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0193549
Feature type
allele
Associated gene
Dmel\Liprin-α
Associated Insertion(s)
Carried in Construct
P{UAS-HA-Liprin-α.H}
Also Known As
UAS-HA-Liprin-α
Key Links
Transgenic product class
cDNA
(Hofmeyer et al., 2006)
wild_type
(Hofmeyer et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Hofmeyer et al., 2006)
wild_type
(Hofmeyer et al., 2006)
Mutagen
in vitro construct
(Hofmeyer et al., 2006)
Progenitor genotype
Liprin-αUAS.cHa
(Hofmeyer et al., 2006)
Carried in construct
P{UAS-HA-Liprin-α.H}
Cytology
Description

UASt regulatory sequences drive expression of the full-length Liprin-α cDNA clone LD27334, with a Tag:HA tag inserted at the N-terminal end of the open reading frame.

(Hofmeyer et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Liprin-α
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Liprin-αScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4Act.PU in RhoGAP100FCD R7 photoreceptor cell clones partially suppresses the failure of the axon terminals to contact the M6 layer of the medulla. The later tendency for R7 axons that do reach the M6 layer to project extensions is not suppressed.

      (Holbrook et al., 2012)

      Overexpression of Liprin-αScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4elav-C155 or Scer\GAL4GMR.PF in a Lar2127/LarC12 mutant background partially restores R7 targeting.

      (Hofmeyer et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4elav-C155/Liprin-αUAS.Tag:HA rescues Liprin-αoos

      (Hofmeyer et al., 2006)
      Comments

      Expression of Liprin-αScer\UAS.T:Ivir\HA1 in the neurons, under the control of Scer\GAL4elav-C155 rescues aberrant R7 photoreceptor targeting in Liprin-αoos mutants.

      Expression of Liprin-αScer\UAS.T:Ivir\HA1 in R7, R3 and R4 cells, under the control of Scer\GAL4hs.2sev rescues aberrant R7 photoreceptor targeting in Liprin-αoos mutants.

      Expression of Liprin-αScer\UAS.T:Ivir\HA1 in R8 cells, under the control of Scer\GAL4sca-109-68 fails to rescue the R7 targeting defect in Liprin-αoos mutants.

      (Hofmeyer et al., 2006)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Liprin-αScer\UAS.T:Ivir\HA1
      Liprin-αUAS.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (3)