FlyBase Allele Report: Scer\GAL4[Orco.PK]

General Information

Symbol

Scer\GAL4^Orco.PK

Species

S. cerevisiae

Name

Odorant receptor co-receptor promoter construct of Kreher

FlyBase ID

FBal0194262

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{Orco-GAL4.K}

Also Known As

Orco-GAL4, Or83b-GAL4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Kreher et al., 2005)

Progenitor genotype

Carried in construct

P{Orco-GAL4.K}

Cytology

Description

A 7.7 kb PCR product whose 3' end is 0.57 kb upstream of the translation initiation codon of Orco regulates expression of a GAL4 driver.

(Kreher et al., 2005)

Allele components

Component

Use(s)

Regulatory region(s)

Orco

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

larval stage

olfactory receptor neuron

(Kreher et al., 2005)

larval stage -- adult stage

olfactory receptor neuron

(Deng et al., 2011)

adult stage

adult olfactory receptor neuron | subset

(Zhang et al., 2020)

Additional Information

Statement

Reference

Drives expression in olfactory receptor neurons.

(FlyBase Curators, 2017)

ScerGAL4^Orco.PK drives expression in most odorant receptor neurons.

(Deng et al., 2011)

Marker for

adult olfactory receptor neuron

(Zhang et al., 2020)

Reflects expression of

Orco

(Zhang et al., 2020, Deng et al., 2011, Kreher et al., 2005)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal courtship behavior | virgin male, with Ugt36E1^GD1766

(Fraichard et al., 2020)

abnormal memory | adult stage, with mir-980^{sponge.V2.UAS.mCherry}

(Guven-Ozkan et al., 2016)

abnormal neuroanatomy | adult stage | cell non-autonomous | progressive, with Hsap\HTT^{Q138.UAS.mRFP1}

(Babcock and Ganetzky, 2015)

abnormal neuroanatomy | adult stage | progressive, with Hsap\HTT^{Q138.UAS.mRFP1}

(Babcock and Ganetzky, 2015)

abnormal neurophysiology | adult stage, with NPF^KK111846

(Lee et al., 2017)

abnormal neurophysiology | adult stage, with NPFR^GD668

(Lee et al., 2017)

abnormal neurophysiology | adult stage | male, with Ugt36E1^GD1766

(Fraichard et al., 2020)

increased cell death | adult stage | cell non-autonomous | progressive, with Hsap\HTT^{Q138.UAS.mRFP1}

(Babcock and Ganetzky, 2015)

increased cell death | adult stage | progressive, with Hsap\HTT^{Q138.UAS.mRFP1}

(Babcock and Ganetzky, 2015)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

23292

w¹¹¹⁸; P{Orco-GAL4.K}97.1

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Scer\GAL4^Or83b.PK

Scer\GAL4^Orco.PK

Name Synonyms

Odorant receptor 83b promoter construct of Kreher

Odorant receptor co-receptor promoter construct of Kreher

Secondary FlyBase IDs

References (39)

Report Sections

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