FB2026_02 , released June 18, 2026
Allele: Dmel\wts5Y2
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General Information
Symbol
Dmel\wts5Y2
Species
D. melanogaster
Name
FlyBase ID
FBal0194761
Feature type
allele
Associated gene
Dmel\wts
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
    Nature of the Allele
    Allele class

    loss of function allele

    (Nairz et al., 2006)
    Mutagen
    Progenitor genotype
    Cytology
    Description

    Amino acid replacement: D769Y.

    (Nairz, 2006.8.18)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    point_mutation
    3R:30,792,305..30,792,305 [-]
    Nucleotide change:

    G30792305T

    Amino acid change:

    D770Y | wts-PA

    Reported amino acid change:

    D769Y

    Comment:

    Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

    (Nairz, 2006.8.18)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Eyes homozygous for wts5Y2 (generated by the eyFLP method) show overgrowth.

        (Baumgartner et al., 2010)

        wts5Y2 clones in the eye show increased interommatidial space.

        (Nairz et al., 2006)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        NOT suppressed by
        Statement
        Reference

        wts5Y2 has visible | somatic clone phenotype, non-suppressible by kibraUAS.cBa/Scer\GAL4GMR.PF

        (Baumgartner et al., 2010)
        Phenotype Manifest In
        NOT suppressed by
        Statement
        Reference

        wts5Y2 has eye | somatic clone phenotype, non-suppressible by kibraUAS.cBa/Scer\GAL4GMR.PF

        (Baumgartner et al., 2010)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        The eye overgrowth phenotype of eyes homozygous for wts5Y2 (generated by the eyFLP method) is not altered by expression of kibraScer\UAS.cBa under the control of Scer\GAL4GMR.PF.

        (Baumgartner et al., 2010)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer

        H. Stocker

        (Nairz, 2006.8.18)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        warts(5Y2)
        (Nairz, 2006.8.18)
        warts5Y2
        (Nairz et al., 2006)
        wts5Y2
        (Baumgartner et al., 2010)
        Name Synonyms
        Secondary FlyBase IDs
          References (3)