FlyBase Allele Report: Dmel\tsr[S3A.cA.UAS]

General Information

Symbol

Dmel\tsr^S3A.cA.UAS

Species

D. melanogaster

Name

FlyBase ID

FBal0194768

Feature type

allele

Associated gene

Dmel\tsr

Associated Insertion(s)

Carried in Construct

P{UAS-cofilin.S3A}

Key Links

Transgenic product class

missense_variant

(Ang et al., 2006)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

missense_variant

(Ang et al., 2006)

Mutagen

in vitro construct

(Ang et al., 2006)

Progenitor genotype

Carried in construct

P{UAS-cofilin.S3A}

Cytology

Description

Amino acid replacement: S3A.

(Ang et al., 2006)

Nucleotide substitution: T?G.

(Ang et al., 2006)

UASt regulatory sequences drive expression of a mutated form of tsr.

(Ang et al., 2006)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

tsr

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

tsr^S3A.cA.UAS, Scer\GAL4^SG18.1 is a suppressor of abnormal neuroanatomy phenotype of LIMK1^{kd.UAS.Tag:MYC}, Scer\GAL4^SG18.1

(Ang et al., 2006)

Phenotype Manifest In

Suppressor of

Statement

Reference

tsr^S3A.cA.UAS, Scer\GAL4^SG18.1 is a suppressor of antennal lobe phenotype of LIMK1^{kd.UAS.Tag:MYC}, Scer\GAL4^SG18.1

(Ang et al., 2006)

tsr^S3A.cA.UAS, Scer\GAL4^SG18.1 is a suppressor of antennal lobe glomerulus DM6 phenotype of LIMK1^{kd.UAS.Tag:MYC}, Scer\GAL4^SG18.1

(Ang et al., 2006)

tsr^S3A.cA.UAS, Scer\GAL4^SG18.1 is a suppressor of antennal lobe glomerulus VA6 phenotype of LIMK1^{kd.UAS.Tag:MYC}, Scer\GAL4^SG18.1

(Ang et al., 2006)

tsr^S3A.cA.UAS, Scer\GAL4^SG18.1 is a suppressor of antennal lobe glomerulus | ectopic phenotype of LIMK1^{kd.UAS.Tag:MYC}, Scer\GAL4^SG18.1

(Ang et al., 2006)

Additional Comments

Genetic Interactions

Statement

Reference

Coexpression of tsr^{S3A.cA.Scer\UAS} and LIMK1^{kd.Scer\UAS.T:Hsap\MYC}, under the control of Scer\GAL4^SG18.1, suppresses the disruption of glomerular structures and presence of ectopic glomeruli at the midline, seen when LIMK1^{kd.Scer\UAS.T:Hsap\MYC} is expressed alone, in 83% of antennal lobes.

(Ang et al., 2006)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

tsr^{S3A.cA.Scer\UAS}

tsr^S3A.cA.UAS

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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