FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Orct2R107
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General Information
Symbol
Dmel\Orct2R107
Species
D. melanogaster
Name
FlyBase ID
FBal0195377
Feature type
allele
Associated gene
Dmel\Orct2
Associated Insertion(s)
P{?GawB}Orct2R107
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Herranz et al., 2006)
Progenitor genotype
P{GawB}Orct2cald-GAL4
(Herranz et al., 2006)
Associated Insertion(s)
P{?GawB}Orct2R107
Cytology
Description

Mobilization of the P{GawB} element, resulting in insertion of a truncated 9kb P{?GawB} element 411bp upstream of the Orct2 transcription start site.

(Herranz et al., 2006)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Orct2R107 embryos show the characteristic U-shape phenotype of embryos unable to retract the germ band.

      The frequencies and sizes of Orct2R107 clones generated in the wing disc are similar to their twin spots 24 hours after induction. After 48 hours, Orct2R107 clones contain significantly fewer cells and are recovered at a lower frequency. At 72 hours after induction, Orct2R107 clones cannot be recovered.

      Cells in Orct2R107 clones generated by the Minute technique in the wing epithelium are smaller than wild-type cells and differentiate thinner, shorter bristles at the adult wing margin and in the notum.

      (Herranz et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Orct2R107 is rescued by Orct2EP1072

      (Herranz et al., 2006)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Orct2R107
      caldR107
      (Herranz et al., 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)