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General Information
Symbol
Hsap\PINK1UAS.Tag:FLAG
Species
H. sapiens
Name
FlyBase ID
FBal0196253
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-hPINK1
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt sequences drive expression of a cDNA encoding the entire coding sequence of wild type Hsap\PINK1 with a C-terminal Tag:FLAG tag.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Flies overexpressing Hsap\PINK1Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4da.G32 show reduced sensitivity to treatment with paraquat or H2O2 but not 2-mercaptoethanol.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference

Expression of Hsap\PINK1Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4elav.PU rescues the defects in mobilisation of the reserve pool of synaptic vesicles which are seen in Pink1B9 mutant larvae.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Hsap\PINK1Scer\UAS.T:Zzzz\FLAG
Hsap\PINK1UAS.Tag:FLAG
Name Synonyms
Secondary FlyBase IDs
    References (2)