FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\stumpsunspecified
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General Information
Symbol
Dmel\stumpsunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0196825
Feature type
allele
Associated gene
Dmel\stumps
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    (FlyBase Curators, 2025-)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In

        embryonic/larval tracheal section

        (Csiszar et al., 2010)

        embryonic/larval tracheal section, with Scer\GAL4twi.PU, stumps802.Y515F.UAS.Tag:FLAG

        (Csiszar et al., 2010)

        embryonic/larval tracheal section, with Scer\GAL4twi.PU, stumps802.Y515F.Y613F.Y629F.UAS.Tag:FLAG

        (Csiszar et al., 2010)

        embryonic/larval tracheal section, with Scer\GAL4twi.PU, stumpsY515F.Y613F.Y629F.UAS.Tag:FLAG

        (Csiszar et al., 2010)

        embryonic/larval tracheal section, with Scer\GAL4unspecified, stumps802.Y613F.Y629F.UAS.Tag:FLAG

        (Csiszar et al., 2010)

        embryonic/larval tracheal section, with Scer\GAL4unspecified, stumpsFFF.Grb2F.UAS.Tag:FLAG

        (Csiszar et al., 2010)

        embryonic/larval tracheal section, with Scer\GAL4unspecified, stumpsFFF.Y844AA.Y891AA.Grb2F.UAS.Tag:FLAG

        (Csiszar et al., 2010)

        embryonic/larval tracheal section, with Scer\GAL4unspecified, stumpsFFF.Y844AA.Y891AA.UAS.Tag:FLAG

        (Csiszar et al., 2010)

        embryonic/larval tracheal section, with Scer\GAL4unspecified, stumpsFFF.Y844F.Y891F.Grb2F.UAS.Tag:FLAG

        (Csiszar et al., 2010)

        embryonic/larval tracheal section, with Scer\GAL4unspecified, stumpsFFF.Y844F.Y891F.UAS.Tag:FLAG

        (Csiszar et al., 2010)

        embryonic/larval tracheal section, with Scer\GAL4unspecified, stumpsY515F.UAS.Tag:FLAG

        (Csiszar et al., 2010)

        pericardial cell primordium

        (Csiszar et al., 2010)

        pericardial cell primordium, with Scer\GAL4twi.PU, stumps802.Y515F.UAS.Tag:FLAG

        (Csiszar et al., 2010)

        pericardial cell primordium, with Scer\GAL4twi.PU, stumps802.Y515F.Y613F.Y629F.UAS.Tag:FLAG

        (Csiszar et al., 2010)

        pericardial cell primordium, with Scer\GAL4twi.PU, stumpsY515F.Y613F.Y629F.UAS.Tag:FLAG

        (Csiszar et al., 2010)

        pericardial cell primordium, with Scer\GAL4unspecified, stumps802.Y613F.Y629F.UAS.Tag:FLAG

        (Csiszar et al., 2010)

        pericardial cell primordium, with Scer\GAL4unspecified, stumpsFFF.Grb2F.UAS.Tag:FLAG

        (Csiszar et al., 2010)

        pericardial cell primordium, with Scer\GAL4unspecified, stumpsFFF.Y844AA.Y891AA.Grb2F.UAS.Tag:FLAG

        (Csiszar et al., 2010)

        pericardial cell primordium, with Scer\GAL4unspecified, stumpsFFF.Y844AA.Y891AA.UAS.Tag:FLAG

        (Csiszar et al., 2010)

        pericardial cell primordium, with Scer\GAL4unspecified, stumpsFFF.Y844F.Y891F.Grb2F.UAS.Tag:FLAG

        (Csiszar et al., 2010)

        pericardial cell primordium, with Scer\GAL4unspecified, stumpsFFF.Y844F.Y891F.UAS.Tag:FLAG

        (Csiszar et al., 2010)

        pericardial cell primordium, with Scer\GAL4unspecified, stumpsY515F.UAS.Tag:FLAG

        (Csiszar et al., 2010)

        terminal tracheal cell | somatic clone

        (Ghabrial and Krasnow, 2006)
        Detailed Description
        Statement
        Reference

        stumpsunspecified mutant embryos show tracheal and pericardial precursor cell defects.

        No pericardial precursor cell clusters are formed in the mesoderm of stumpsunspecified mutants embryos expressing Scer\GAL4twi.PU>stumps802.Y515F.Y613F.Y629F.Scer\UAS.T:Zzzz\FLAG. No fusions are seen in the dorsal trunk, and other branches of the tracheal system fail almost completely to grow out.

        (Csiszar et al., 2010)

        Mosaic analysis of stumpsunspecified shows a dearth of homozygous terminal cell clones in the tracheal system.

        (Ghabrial and Krasnow, 2006)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Rescued by

        stumpsunspecified is rescued by stumpsUAS.Tag:FLAG/Scer\GAL4twi.PU

        (Csiszar et al., 2010)

        stumpsunspecified is rescued by Scer\GAL4unspecified/stumps802.UAS.Tag:FLAG

        (Csiszar et al., 2010)

        stumpsunspecified is rescued by stumpsY613F.Y629F.UAS.Tag:FLAG/Scer\GAL4unspecified

        (Csiszar et al., 2010)

        stumpsunspecified is rescued by Scer\GAL4unspecified/stumpsFFF.Y844F.UAS.Tag:FLAG

        (Csiszar et al., 2010)
        Partially rescued by

        stumpsunspecified is partially rescued by stumps802.Y613F.Y629F.UAS.Tag:FLAG/Scer\GAL4unspecified

        (Csiszar et al., 2010)

        stumpsunspecified is partially rescued by stumpsY515F.UAS.Tag:FLAG/Scer\GAL4unspecified

        (Csiszar et al., 2010)

        stumpsunspecified is partially rescued by stumps802.Y515F.UAS.Tag:FLAG/Scer\GAL4twi.PU

        (Csiszar et al., 2010)

        stumpsunspecified is partially rescued by stumpsY515F.Y613F.Y629F.UAS.Tag:FLAG/Scer\GAL4twi.PU

        (Csiszar et al., 2010)

        stumpsunspecified is partially rescued by stumpsFFF.Y844F.Y891F.UAS.Tag:FLAG/Scer\GAL4unspecified

        (Csiszar et al., 2010)

        stumpsunspecified is partially rescued by Scer\GAL4unspecified/stumpsFFF.Grb2F.UAS.Tag:FLAG

        (Csiszar et al., 2010)

        stumpsunspecified is partially rescued by Scer\GAL4unspecified/stumpsFFF.Y844AA.Y891AA.UAS.Tag:FLAG

        (Csiszar et al., 2010)

        stumpsunspecified is partially rescued by Scer\GAL4unspecified/stumpsFFF.Y844AA.Y891AA.Grb2F.UAS.Tag:FLAG

        (Csiszar et al., 2010)
        Not rescued by

        stumpsunspecified is not rescued by stumps802.Y515F.Y613F.Y629F.UAS.Tag:FLAG/Scer\GAL4twi.PU

        (Csiszar et al., 2010)

        stumpsunspecified is not rescued by Scer\GAL4unspecified/stumpsFFF.Y844F.Y891F.Grb2F.UAS.Tag:FLAG

        (Csiszar et al., 2010)
        Comments

        Expression of stumpsY844AA.Y891AA.Grb2F.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4unspecified partially rescues the tracheal and pericardial precursor cell defects in stumpsunspecified mutant embryos.

        Expression of stumpsY844AA.Y891AA.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4unspecified partially rescues the tracheal and pericardial precursor cell defects in stumpsunspecified mutant embryos.

        Expression of stumpsY844F.Y891F.Grb2F.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4unspecified fails to rescue the tracheal and pericardial precursor cell defects in stumpsunspecified mutant embryos.

        Expression of stumpsGrb2F.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4unspecified partially rescues the tracheal and pericardial precursor cell defects in stumpsunspecified mutant embryos.

        Expression of stumpsY844F.Y891F.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4unspecified partially rescues the tracheal and pericardial precursor cell defects in stumpsunspecified mutant embryos.

        Expression of stumpsY844F.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4unspecified rescues the tracheal and pericardial precursor cell defects in stumpsunspecified mutant embryos.

        Expression of stumps802.Y515F.Y613F.Y629F.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4twi.PU fails to rescue the tracheal and pericardial precursor cell defects in stumpsunspecified mutant embryos.

        Expression of stumpsY515F.Y613F.Y629F.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4twi.PU partially rescues the tracheal and pericardial precursor cell defects in stumpsunspecified mutant embryos.

        Expression of stumps802.Y515F.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4twi.PU partially rescues the tracheal and pericardial precursor cell defects in stumpsunspecified mutant embryos.

        Expression of stumps802.Y613F.Y629F.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4unspecified partially rescues the tracheal and pericardial precursor cell defects in stumpsunspecified mutant embryos.

        Expression of stumpsY515F.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4unspecified partially rescues the tracheal and pericardial precursor cell defects in stumpsunspecified mutant embryos.

        Expression of stumpsY613F.Y629F.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4unspecified rescues the tracheal and pericardial precursor cell defects in stumpsunspecified mutant embryos.

        Expression of stumps802.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4unspecified rescues the tracheal and pericardial precursor cell defects in stumpsunspecified mutant embryos.

        Expression of stumpsScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4twi.PU rescues the tracheal and pericardial precursor cell defects in stumpsunspecified mutant embryos.

        (Csiszar et al., 2010)
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        stumpsunspecified
        Name Synonyms
        Secondary FlyBase IDs
          References (3)