FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\DJ-1αk04204
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General Information
Symbol
Dmel\DJ-1αk04204
Species
D. melanogaster
Name
FlyBase ID
FBal0197151
Feature type
allele
Associated gene
Dmel\DJ-1α
Associated Insertion(s)
P{lacW}shotk04204
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{lacW}shotk04204
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{lacW}
    Encoded product / tool
    lacZ
    Tagged with
    Tag:NLS(P)
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressed by
        Statement
        Reference

        DJ-1αk04204 has lethal | recessive phenotype, suppressible by Hsap\PARK7UAS.cKa/Scer\GAL4arm.PS

        (Kim et al., 2005)
        Enhancer of
        Statement
        Reference

        DJ-1α[+]/DJ-1αk04204 is an enhancer of visible phenotype of PtenUAS.cKa, Scer\GAL4GMR.PF

        (Kim et al., 2005)
        Suppressor of
        Statement
        Reference

        DJ-1αk04204 is a suppressor of visible phenotype of RetMEN2B.GMR

        (Aron et al., 2010)
        Phenotype Manifest In
        Enhancer of
        Statement
        Reference

        DJ-1α[+]/DJ-1αk04204 is an enhancer of eye phenotype of PtenUAS.cKa, Scer\GAL4GMR.PF

        (Kim et al., 2005)
        Suppressor of
        Statement
        Reference

        DJ-1αk04204 is a suppressor of eye | adult stage phenotype of RetMEN2B.GMR

        (Aron et al., 2010)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        DJ-1αk04204 significantly suppresses the small rough eye phenotype in RetMEN2B.GMR flies.

        (Aron et al., 2010)

        Flies expressing PtenScer\UAS.cKa under the control of Scer\GAL4GMR.PF show an increase in roughness and a further slight decrease in eye size if they are also carrying DJ-1αk04204/+.

        (Kim et al., 2005)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        DJ-1αk04204
        l(2)k04204
        (Kim et al., 2005)
        Name Synonyms
        Secondary FlyBase IDs
          References (2)