FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\dallyΔGAG.UAS
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General Information
Symbol
Dmel\dallyΔGAG.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0197579
Feature type
allele
Associated gene
Dmel\dally
Associated Insertion(s)
Carried in Construct
P{UAS-dallyΔGAG}
Key Links
Transgenic product class
missense_variant
(Kirkpatrick et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Kirkpatrick et al., 2006)
Mutagen
in vitro construct
(Kirkpatrick et al., 2006)
Progenitor genotype
Carried in construct
P{UAS-dallyΔGAG}
Cytology
Description

Amino acid replacement: S569A.

(Kirkpatrick et al., 2006)

UASt regulatory sequences drive expression of the glycosaminoglycan-deficient form of dally.

(Kirkpatrick et al., 2006)

Amino acid replacement: S573A.

(Kirkpatrick et al., 2006)

Amino acid replacement: S549A.

(Kirkpatrick et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dally
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of dallyΔGAG.Scer\UAS in the wing, under the control of Scer\GAL4en-e16E, results in disruption of the anterior crossvein.

      Unlike overexpression of wild-type dally, expression of dallyΔGAG.Scer\UAS in the eye, driven by Scer\GAL4ey.PH, does not result in overgrowth or a change in photoreceptor number per ommatidium. However, it does result in a severely disorganized ommatidial structure, which is not seen when wild-type dally is overexpressed.

      (Kirkpatrick et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4A9/dallyΔGAG.UAS partially rescues dallyΔP-527/dallygem

      (Kirkpatrick et al., 2006)

      Scer\GAL4A9/dallyΔGAG.UAS partially rescues Df(3L)Scf-R6/dallygem

      (Kirkpatrick et al., 2006)

      Scer\GAL4A9/dallyΔGAG.UAS partially rescues dally80/Df(3L)Scf-R6

      (Kirkpatrick et al., 2006)

      Scer\GAL4A9/dallyΔGAG.UAS partially rescues dallygem

      (Kirkpatrick et al., 2006)
      Comments

      Expression of dallyΔGAG.Scer\UAS under the control of Scer\GAL4A9 partially rescues the phenotypes of dallygem, dallygem/Df(3L)Scf-R6, dallygem/dallyΔP-527 and dally80/Df(3L)Scf-R6 mutants. The transgene substantially restores chemosensory bristle numbers in the wing margin, almost fully rescues the formation of wing vein L5, almost fully restores the formation of the anterior dorsocentral bristles on the notum without inducing the formation of extra ones for all mutants. However, it fails to restore formation of the posterior supraalar bristles.

      (Kirkpatrick et al., 2006)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      dallyΔGAG.Scer\UAS
      dallyΔGAG.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)