FlyBase Allele Report: Dmel\stmA[EGFP]

General Information

Symbol

Dmel\stmA^EGFP

Species

D. melanogaster

Name

FlyBase ID

FBal0197755

Feature type

allele

Associated gene

Dmel\stmA

Associated Insertion(s)

Carried in Construct

P{stmA-EGFP.H}

Also Known As

rbo-egfp

Key Links

Transgenic product class

genomic_DNA

(Huang et al., 2004)

wild_type

(Huang et al., 2004)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

genomic_DNA

(Huang et al., 2004)

wild_type

(Huang et al., 2004)

Mutagen

in vitro construct

(Huang et al., 2004)

Progenitor genotype

Carried in construct

P{stmA-EGFP.H}

Cytology

Description

Contains a genomic stmA fragment tagged with EGFP.

(Huang et al., 2004)

Allele components

Component

Use(s)

Regulatory region(s)

stmA

Encoded product / tool

stmA

Tagged with

EGFP

green fluorescent protein

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

olfactory receptor neuron of third segment of antenna

(Kain et al., 2009)

adult antennal lobe

(Kain et al., 2009)

adult mushroom body

(Kain et al., 2009)

Additional Information

Statement

Reference

Expression is observed in the sensory neurons of the third antennal segment and throughout the adult antennal lobe. Expression is also observed in all lobes of the adult mushroom body.

(Kain et al., 2009)

Marker for

Reflects expression of

stmA

(Kain et al., 2009)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

viable, with stmA¹/stmA^rev499

(Vijayakrishnan et al., 2010)

Phenotype Manifest In

Detailed Description

Statement

Reference

stmA^rev499/stmA¹ mutants carrying stmA^{S358A.T:Avic\GFP-EGFP} are viable.

(Vijayakrishnan et al., 2010)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

stmA^EGFP rescues stmA¹/stmA^rev499

(Vijayakrishnan et al., 2009)

stmA^EGFP rescues stmA¹/Df(2R)H3D3

(Huang et al., 2006)

stmA^EGFP rescues stmA¹

(Huang et al., 2006)

stmA^EGFP rescues stmA¹/stmA^18-2

(Huang et al., 2006)

stmA^EGFP rescues stmA¹/stmA^rev499

(Huang et al., 2006)

stmA^EGFP rescues stmA¹/stmA^rev499

(Huang et al., 2004)

Fails to rescue

stmA^EGFP fails to rescue stmA^rev499

(Vijayakrishnan et al., 2010)

Comments

Endocytosis, which is defective in stmA¹ animals, is restored to wildtype levels in stmA¹/stmA^rev499; stmA^{T:Avic\GFP-EGFP}/stmA^{T:Avic\GFP-EGFP} animals.

(Vijayakrishnan et al., 2009)

A single copy of stmA^{T:Avic\GFP-EGFP} fully recues the behavioural paralysis found in all of the homozygous stmA¹, heterozygous stmA¹/stmA^rev499, stmA¹/stmA^18-2, and stmA¹/Df(2R)H3D3 mutants.

(Huang et al., 2006)

The temperature sensitive electroretinogram defect seen in stmA¹/stmA^rev499 flies at 37^oC is completely rescued by stmA^{T:Avic\GFP-EGFP}.

(Huang et al., 2004)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

rbo-egfp

(Vijayakrishnan et al., 2009)

stmA^EGFP

stmA^{T:Avic\GFP-EGFP}

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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