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General Information
Symbol
Dmel\fweGD4616
Species
D. melanogaster
Name
FlyBase ID
FBal0204968
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Adults expressing fweGD4616 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

In competition with dmαTub84B.PBb expressing cells, cell clones expressing fweGD4616 driven by Scer\GAL4αTub84B.PBb survive significantly better than wild-type cells in a growing population of wing imaginal disc cells.

Clones of cells expressing fweGD4616 under the control of Scer\GAL4Act5C.PI in the wing imaginal disc epithelium tend to die 96 hours after clone induction when surrounded by wild-type cells.

Cells of the posterior compartment of the wing imaginal disc expressing fweGD4616 under the control of Scer\GAL4en-e16E do not show signs of increased apoptosis compared to controls. Compartment size is not affected by expression of fweGD4616 under the control of Scer\GAL4en-e16E.

Expression under the control of Scer\GAL4pnr-MD237 results in loss of bristles on the notum in 10-20% of the Scer\GAL4pnr-MD237 expression domain.

External Data
Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT Enhancer of
Suppressor of
NOT Suppressor of
Phenotype Manifest In
Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

Co-expression of fweGD4616 with egrScer\UAS.cMa driven by Scer\GAL4GMR.PF has no effect on the eye ablation phenotype resulting from egrScer\UAS.cMa-overexpression.

Expression of fweGD4616 driven by Scer\GAL4en-e16E significantly reduces the expansion of dmαTub84B.PBb-overexpressing clones in the posterior compartment of wing imaginal discs.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 1 )
Crossreferences
Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
CG6151GD4616
flowerGD4616
fweGD4616
Name Synonyms
Secondary FlyBase IDs
    References (8)