FlyBase Allele Report: Dmel\Lsp1α[GD6490]

FB2026_02 , released June 18, 2026

FB2026_02 , released June 18, 2026

Allele: Dmel\Lsp1α^GD6490

General Information

Symbol

Dmel\Lsp1α^GD6490

Species

D. melanogaster

Name

FlyBase ID

FBal0207524

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

Transgenic product class

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

(Dickson et al., 2007.7.18)

Progenitor genotype

Carried in construct

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Dickson et al., 2007.7.18)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

(Neely et al., 2010)

viable, with Scer\GAL4^Mef2.PR

(Schnorrer et al., 2010)

viable, with Scer\GAL4^pnr-MD237

(Mummery-Widmer et al., 2009)

Phenotype Manifest In

Detailed Description

Statement

Reference

Adults expressing Lsp1α^GD6490 under the control of Scer\GAL4^elav.PLu (in the presence of Dcr-2^Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

(Neely et al., 2010)

External Data

Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development

6490

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Lsp1α^GD6490, Lsp2^KK115182, Scer\GAL4^apolpp.PB has male semi-fertile phenotype

(Valzania et al., 2024)

Lsp1α^GD6490, Lsp2^KK115182, Scer\GAL4^apolpp.PB has abnormal starvation stress response | adult stage phenotype

(Valzania et al., 2024)

Lsp1α^GD6490, Lsp2^KK115182, Scer\GAL4^apolpp.PB has partially lethal phenotype

(Valzania et al., 2024)

Lsp1α^GD6490, Lsp2^KK115182, Scer\GAL4^apolpp.PB has increased body size | P-stage phenotype

(Valzania et al., 2024)

Lsp1α^GD6490, Lsp2^KK115182, Scer\GAL4^apolpp.PB has decreased rate of adult locomotory behavior | larval stage phenotype

(Valzania et al., 2024)

Lsp1α^GD6490, Lsp2^KK115182, Scer\GAL4^apolpp.PB has abnormal developmental rate phenotype

(Valzania et al., 2024)

Lsp1α^GD6490, Lsp2^KK115182, Scer\GAL4^apolpp.PB has increased body size | adult stage phenotype

(Valzania et al., 2024)

Lsp1α^GD6490, Lsp2^KK115182, Scer\GAL4^apolpp.PB has short lived phenotype

(Valzania et al., 2024)

Lsp1α^GD6490, Lsp2^KK115182, Scer\GAL4^apolpp.PB has abnormal size phenotype

(Valzania et al., 2024)

Lsp1α^GD6490, Lsp2^KK115182, Scer\GAL4^apolpp.PB has female semi-fertile phenotype

(Valzania et al., 2024)

Lsp1α^GD6490, Lsp2^KK115182, Scer\GAL4^apolpp.PB has increased body size | larval stage phenotype

(Valzania et al., 2024)

Phenotype Manifest In

Other

Statement

Reference

Lsp1α^GD6490, Lsp2^KK115182, Scer\GAL4^apolpp.PB has wing phenotype

(Valzania et al., 2024)

Lsp1α^GD6490, Lsp2^KK115182, Scer\GAL4^apolpp.PB has wing disc phenotype

(Valzania et al., 2024)

Lsp1α^GD6490, Lsp2^KK115182, Scer\GAL4^apolpp.PB has embryonic/larval hemolymph | larval stage phenotype

(Valzania et al., 2024)

Lsp1α^GD6490, Lsp2^KK115182, Scer\GAL4^apolpp.PB has adult hemolymph phenotype

(Valzania et al., 2024)

Lsp1α^GD6490, Lsp2^KK115182, Scer\GAL4^apolpp.PB has adult abdomen phenotype

(Valzania et al., 2024)

Lsp1α^GD6490, Lsp2^KK115182, Scer\GAL4^apolpp.PB has sarcomere phenotype

(Valzania et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

v14898

w¹¹¹⁸; P{GD6490}v14898

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 1 )

Linkouts

Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development

6490

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Lsp1α^GD6490

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections