UASt regulatory sequences drive expression of an inverted repeat.
Expression via "HHLT-gal4" or Scer\GAL4Hml.Δ or Scer\GAL4dome-PG14 results in loss of progenitor cells in the primary lobes of the larval lymph gland. ("HHLT-gal4" is a combination of Scer\GAL4HCH.Hand and Scer\GAL4Hml.Δ that express in early lymph gland blood cells (hemocytes) and circulating and sessile blood cells, respectively, and incorporates Scer\GAL4Scer\FRT.Rnor\CD2.Act5C to maintain expression in the lymph gland after Scer\GAL4HCH.Hand is down-regulated.)
Adults expressing Noa36GD6838 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Expression of Noa36GD6838 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) results in viable flies or complete lethality, depending on the particular P{GD6838} insertion line used.
Expression under the control of Scer\GAL4Mef2.PR results in late pupal lethality.
Expression under the control of Scer\GAL4pnr-MD237 results in lethality at the pupal stage or semi-lethality during the adult stage, depending on the insertion line used.
Expression under the control of Scer\GAL4pnr-MD237 results in the absence of 80-90% of the Scer\GAL4pnr-MD237-expressing area of the notum.