Hemocytes trans-migrate properly from the head to tail in embryos expressing Rho1GD4726 under the control of Scer\GAL4Pxn.PS. However, fewer of the tail hemocytes migrate anteriorly along the midline in the knock-down line than in wild-type.
Compared with wild-type, posterior hemocytes in Scer\GAL4Pxn.PS>Rho1GD4726 embryos exhibit severe reduction in cellular protrusion area. The anterior hemocytes of the same genotype also show a moderate reduction in cellular protrusion area. The number of vacuoles present in both the anterior and posterior hemocyte cell bodies is increased relative to wild-type.
Eye-antennal disc clones expressing Rho1GD4726 under the control of Scer\GAL4tub.PU exhibit defects in differentiation and cell morphology, but clone size is not significantly affected as compared to control clones.
Expression under the control of Scer\GAL4Mef2.PR results in late larval lethality.
Expression of Rho1GD4726 under the control of Scer\GAL4ppl.PP results in animals with a dorsal cleft in the abdominal cuticle (most of these animals die in the puparium, with approximately 12% eclosing).
Expression of Rho1GD4726 in the dorsal compartment of the wing disc (under the temperature-regulated control of Scer\GAL4ap-md544 by Scer\GAL80ts.αTub84B) results in highly elongated apical-basal cell length in mutant cells compared with control cells.