UASt regulatory sequences drive expression of an inverted repeat.
Expression of ctpGD4688 under the control of Scer\GAL4en.PU results in a significant reduction in the size of the posterior compartment (the region of Scer\GAL4en.PU expression) of the wing compared to the anterior compartment.
Mitotic index is increased in the posterior compartment (compared to the anterior compartment) of the wing disc of animals expressing ctpGD4688 under the control of Scer\GAL4en.PU. There is an increase in the number of apoptotic cells in the posterior compartment compared to the anterior compartment.
Expression under the control of Scer\GAL41407 results in loss of neuroblasts in the larval brain associated with increased size of the remaining neuroblasts.
Expression under the control of Scer\GAL41407 results in shorter neuroblast lineages (less daughter cells per neuroblast) in the larval brain compared to controls.
Expression under the control of Scer\GAL41407 results in mild defects in the shape of ganglion mother cells in the larval brain.
Expression under the control of Scer\GAL41407 results in mild defects in the shape of neuroblasts in the larval brain.
Adults expressing ctpGD4688 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) can show significantly reduced avoidance of noxious temperature (46[o]C) compared to control flies, depending on the particular P{GD4688} insertion line used.
Adults expressing ctpGD4688 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) show no significant change in the kinetics of high temperature (46[o]C) induced paralysis compared to control flies.
Expression under the control of Scer\GAL4Mef2.PR results in early pupal lethality.
Expression under the control of Scer\GAL4pnr-MD237 may result in semi-lethality, depending on the insertion line used.
Expression under the control of Scer\GAL4pnr-MD237 results in external sensory organs consisting of empty or multiple sockets in 0% or 30-40% of the Scer\GAL4pnr-MD237 expression domain of the notum, depending on the insertion line used.
Expression under the control of Scer\GAL4pnr-MD237 results in bristle morphology defects on the notum in 100% or 90-100% of the Scer\GAL4pnr-MD237 expression domain, depending on the insertion line used.
Expression under the control of Scer\GAL4pnr-MD237 results in the absence of 10-20% or 20-30% of the Scer\GAL4pnr-MD237-expressing area of the notum, depending on the insertion line used.